ArticleArchives of disease in childhood. Fetal and neonatal edition2016
Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants.
Article in Archives of disease in childhood. Fetal and neonatal edition, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00009633 (Follow-up Visit of High Risk Infants), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Follow-up Visit of High Risk Infants
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The effects of different types of prenatal exercise on neonatal outcomes: a systematic review and network meta-analysis.Frontiers in physiology · 2026Pooled it
- Machine learning techniques for predicting neurodevelopmental impairments in premature infants: a systematic review.Frontiers in artificial intelligence · 2025Pooled it
- Predicting the outcomes of preterm neonates beyond the neonatal intensive care unit: What are we missing?Pediatric research · 2021Pooled it
- Article
- Birth Weight Stratification May Clarify Developmental Effects of Parent-Delivered Interventions in Preterm Infants: Letter to the Editor.Health science reports · 2026Article
- Group-based trajectory modelling and interpretable machine learning to identify factors associated with neurodevelopmental trajectories in preterm infants.BMC pediatrics · 2026Article
- Cognitive, language and motor developmental patterns of extremely preterm children up to 2 years of age: a descriptive approach.Frontiers in psychology · 2025Article
- Protective Effects of Early Neonatal Methylxanthine Treatment on Cognitive and Language Outcomes in Premature Infants with and without High-Risk Perinatal Factors.Developmental neuroscience · 2025Article
- Article
- Risk Factors for Neurodevelopmental Impairment at 2- and 5-Years Corrected Age in Preterm Infants with Established Bronchopulmonary Dysplasia.Neonatology · 2024Article
- Growth and Duration of Inflammation Determine Short- and Long-Term Outcome in Very-Low-Birth-Weight Infants Requiring Abdominal Surgery.Nutrients · 2023Article
- Active Treatment of Infants Born at 22-25 Weeks of Gestation in California, 2011-2018.The Journal of pediatrics · 2022Observational
- Neonatal Outcome and Treatment Perspectives of Preterm Infants at the Border of Viability.Children (Basel, Switzerland) · 2022Review
- Increased Risk for Respiratory Complications in Male Extremely Preterm Infants: A Propensity Score Matching Study.Frontiers in endocrinology · 2022Article
- The Future of Outcome Prediction for Preterm Infants in the Neonatal ICU.American journal of respiratory and critical care medicine · 2022Article
- Association of Blood Donor Sex and Age With Outcomes in Very Low-Birth-Weight Infants Receiving Blood Transfusion.JAMA network open · 2021Article
- Developmental Trajectories in Very Preterm Born Children Up to 8 Years: A Longitudinal Cohort Study.Frontiers in pediatrics · 2021Article
- Predictive Modeling for Perinatal Mortality in Resource-Limited Settings.JAMA network open · 2020Article
- Review
- Genetic and environmental factors affecting birth size variation: a pooled individual-based analysis of secular trends and global geographical differences using 26 twin cohorts.International journal of epidemiology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundThe risk of poor outcomes in preterm infants is primarily determined by birthweight (BW) and gestational age (GA). It is not known whether BW is a better outcome predictor than GA.
objectiveTo test whether BW is better than GA (measured in days, rather than completed weeks) for prediction of neurodevelopmental impairment (NDI) and death. DESIGN/
methodsExtremely preterm infants born at the National Institute of Child Health and Human Development (NICHD) Neonatal Research Network centres between 1998 and 2009 were studied. For the unadjusted analysis, the associations of GA (in days based on best obstetrical estimate) and BW (in grams) with NDI or death were compared using area under the curve (AUC). Adjusted analyses were performed using birth year, sex, race, antenatal steroids, singleton birth, pre-eclampsia, Apgar score at 5 min and small for GA as covariates.
results10 652 preterm infants (89%) had outcome data at 18-22 months' corrected age. The mean BW was 678 g (SD: 155) and the mean GA was 173 days (SD: 10) or 24
conclusionBoth BW in grams and GA in days are good predictors of NDI and death in a preterm population selected on the basis of reliable GA. TRIAL REGISTRATION NUMBER: NCT00009633.
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