ArticleJournal of speech, language, and hearing research : JSLHR2016
Pragmatic Language Features of Mothers With the FMR1 Premutation Are Associated With the Language Outcomes of Adolescents and Young Adults With Fragile X Syndrome.
Article in Journal of speech, language, and hearing research : JSLHR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 22 citations in OpenAlex.
- Neural Sensitivity to Conversational Inter-Speaker Gaps in the Broad Autism Phenotype.Psychophysiology · 2026Article
- Capturing Phenotypic Heterogeneity in Differentiated Sensory Processing Profiles: Non-Syndromic Autism and Fragile X Syndrome.Autism : the international journal of research and practice · 2026Article
- Discourse Marker Use in Mothers of Autistic Individuals and FMR1 Premutation Carriers.Journal of autism and developmental disorders · 2026Article
- The impact of individual factors on linguistic alignment of autistic boys and their mothers.Autism : the international journal of research and practice · 2026Article
- Pre-trained artificial intelligence language model represents pragmatic language variability central to autism and genetically related phenotypes.Autism : the international journal of research and practice · 2025Article
- Social Communication Delay in an Unbiased Sample of Preschoolers With theJournal of speech, language, and hearing research : JSLHR · 2024Article
- Review
- Maternal Pragmatic Language Difficulties in the FMR1 Premutation and the Broad Autism Phenotype: Associations with Individual and Family Outcomes.Journal of autism and developmental disorders · 2022Article
- The FMR1 Premutation Phenotype and Mother-Youth Synchrony in Fragile X Syndrome.American journal on intellectual and developmental disabilities · 2021Article
- Family as a Context for Child Development: Mothers with the FMR1 Premutation and Their Children with Fragile X Syndrome.Seminars in speech and language · 2021Review
- The Phenotypic Profile Associated With theFrontiers in psychiatry · 2021Article
- A Unique Visual Attention Profile Associated With theFrontiers in genetics · 2021Article
- A Longitudinal Study of Parent-Child Interactions and Language Outcomes in Fragile X Syndrome and Other Neurodevelopmental Disorders.Frontiers in psychiatry · 2021Article
- Syntactic Ability of Girls With Fragile X Syndrome: Phonological Memory and Discourse Demands on Complex Sentence Use.American journal on intellectual and developmental disabilities · 2019Article
- Vagal Tone as a Putative Mechanism for Pragmatic Competence: An Investigation of Carriers of the FMR1 Premutation.Journal of autism and developmental disorders · 2019Article
- Curvilinear Association Between Language Disfluency andFrontiers in genetics · 2018Article
- Altered sensitivity to social gaze in the FMR1 premutation and pragmatic language competence.Journal of neurodevelopmental disorders · 2017Article
- Reduced vagal tone in women with theJournal of neurodevelopmental disorders · 2017Article
- Impaired eye contact in the FMR1 premutation is not associated with social anxiety or the broad autism phenotype.The Clinical neuropsychologistArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposePragmatic language difficulties have been documented as part of the FMR1 premutation phenotype, yet the interplay between these features in mothers and the language outcomes of their children with fragile X syndrome is unknown. This study aimed to determine whether pragmatic language difficulties in mothers with the FMR1 premutation are related to the language development of their children.
methodTwenty-seven mothers with the FMR1 premutation and their adolescent/young adult sons with fragile X syndrome participated. Maternal pragmatic language violations were rated from conversational samples using the Pragmatic Rating Scale (Landa et al., 1992). Children completed standardized assessments of vocabulary, syntax, and reading.
resultsMaternal pragmatic language difficulties were significantly associated with poorer child receptive vocabulary and expressive syntax skills, with medium effect sizes.
conclusionsThis work contributes to knowledge of the FMR1 premutation phenotype and its consequences at the family level, with the goal of identifying modifiable aspects of the child's language-learning environment that may promote the selection of treatments targeting the specific needs of families affected by fragile X. Findings contribute to our understanding of the multifaceted environment in which children with fragile X syndrome learn language and highlight the importance of family-centered intervention practices for this group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.