ArticlePloS one2016
Internal Jugular Vein Cross-Sectional Area Enlargement Is Associated with Aging in Healthy Individuals.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Integrative cardiovascular dose-response to graded lower-body negative pressure.Experimental physiology · 2025Article
- Ultrasound Evaluation of Internal Jugular Venous Insufficiency and Its Association with Cognitive Decline.Diagnostics (Basel, Switzerland) · 2025Article
- Ultrasonographic assessment of right internal jugular vein dimensions following passive legs elevation versus hepatic compression: a cross-sectional study.BMC anesthesiology · 2025Article
- Observational
- Jugular venous flow dynamics during acute weightlessness.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Risk factors of hemodialysis catheter dysfunction in patients undergoing continuous renal replacement therapy: a retrospective study.BMC nephrology · 2023Article
- B-mode and color Doppler ultrasonography of normal external jugular vein in donkeys (Equus asinus).BMC veterinary research · 2022Article
- Cardiac and Respiratory Influences on Intracranial and Neck Venous Flow, Estimated Using Real-Time Phase-Contrast MRI.Biosensors · 2022Article
- Breath-holding could improve visualization of the internal jugular veins by ultrasound guidance in obese patients with trauma.Scandinavian journal of trauma, resuscitation and emergency medicine · 2022Article
- Sex-dependent jugular vein optical attenuation and distension during head-down tilt and lower body negative pressure.Physiological reports · 2022Article
- Anatomical Morphology Analysis of Internal Jugular Veins and Factors Affecting Internal Jugular Vein Size.Medicina (Kaunas, Lithuania) · 2020Article
- Venous and Arterial Responses to Partial Gravity.Frontiers in physiology · 2020Article
- Ultrasonographic assessment of normal jugular veins in Standardbred horses.BMC veterinary research · 2019Article
- Abnormal venous postural control: multiple sclerosis-specific change related to gray matter pathology or age-related neurodegenerative phenomena?Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2019Article
- Dural arteriovenous fistula of the lateral foramen magnum region: A review.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2018Review
- Understanding jugular venous outflow disturbance.CNS neuroscience & therapeutics · 2018Review
- Lower Arterial Cross-Sectional Area of Carotid and Vertebral Arteries and Higher Frequency of Secondary Neck Vessels Are Associated with Multiple Sclerosis.AJNR. American journal of neuroradiology · 2018Article
- Neck Vessel Cross-Sectional Area Measured with MRI: Scan-Rescan Reproducibility for Longitudinal Evaluations.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2018Article
- Jugular Anomalies in Multiple Sclerosis Are Associated with Increased Collateral Venous Flow.AJNR. American journal of neuroradiology · 2017Article
- Age differences in arterial and venous extra-cerebral blood flow in healthy adults: contributions of vascular risk factors and genetic variants.Brain structure & function · 2017Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInternal jugular vein (IJV) narrowing has been implicated in central nervous system pathologies, however normal physiological age- and gender-related IJV variance in healthy individuals (HIs) has not been adequately assessed.
objectivesWe assessed the relationship between IJV cross-sectional area (CSA) and aging. MATERIALS AND
methodsThis study involved 193 HIs (63 males and 130 females) who received 2-dimensional magnetic resonance venography at 3T. The minimum CSA of the IJVs at cervical levels C2/C3, C4, C5/C6, and C7/T1 was obtained using a semi-automated contouring-thresholding technique. Subjects were grouped by decade. Pearson and partial correlation (controlled for cardiovascular risk factors, including hypertension, heart disease, smoking and body mass index) and analysis of variance analyses were used, with paired t-tests comparing side differences.
resultsMean right IJV CSA ranges were: in males, 41.6 mm2 (C2/C3) to 82.0 mm2 (C7/T1); in females, 38.0 mm2 (C2/C3) to 62.3 mm2 (C7/T1), while the equivalent left side ranges were: in males, 28.0 mm2 (C2/C3) to 52.2 mm2 (C7/T1); in females, 27.2 mm2 (C2/C3) to 47.8 mm2 (C7/T1). The CSA of the right IJVs was significantly larger (p<0.001) than the left at all cervical levels. Controlling for cardiovascular risk factors, the correlation between age and IJV CSA was more robust in males than in the females for all cervical levels.
conclusionsIn HIs age, gender, hand side and cervical location all affect IJV CSA. These findings suggest that any definition of IJV stenosis needs to account for these factors.
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