Evidence map›Paper›PMID 26895323›Full record

Observational studyNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2016

Use of herbal remedies by multiple sclerosis patients: a nation-wide survey in Italy.

A Loraschi, P Bellantonio, F Bortolon, R Capra, P Cavalla, G Costantino, A Lugaresi, V Martinelli, M G Marrosu, F Patti and 8 more

Abstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Immunomodulatory Potential of Cannabidiol in Multiple Sclerosis: a Systematic Review.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Advances in clinical neurology through the journal "Neurological Sciences" (2015-2016).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2017
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

A LoraschiCenter for Research in Medical Pharmacology, University of Insubria, Via Ottorino Rossi n. 9, 21100, Varese, VA, Italy.
P BellantonioMultiple Sclerosis Center, IRCCS Neuromed, Pozzilli, IS, Italy.
F BortolonMultiple Sclerosis Centre, "San Bortolo" Hospital, Vicenza, Italy.
R CapraMultiple Sclerosis Center, Montichiari Hospital, Spedali Civili of Brescia, Brescia, Italy.
P Cavalla1 Division of Neurology, Multiple Sclerosis Centre, A.O.U. City of Health and Science of Turin, Turin, Italy.
G CostantinoStruttura Semplice "Sclerosi multipla" Az Ospedale-Università "Ospedali riuniti", Foggia, Italy.
A LugaresiDepartment of Neuroscience, Imaging and Clinical Sciences, University G. d'Annunzio, Chieti, Italy.
V MartinelliDepartment of Neurology, San Raffaele Hospital, Milan, Italy.
M G MarrosuDepartment of Medical Sciences, University of Cagliari, Cagliari, Italy.
F PattiDepartment of Medical and Surgical Science and Advanced Technologies, GF Ingrassia, Neurosciences Section, Multiple Sclerosis Center, University of Catania, Catania, Italy.
M RottoliMultiple Sclerosis Center of Bergamo, USS Malattie Autoimmuni, Azienda Ospedaliera Papa Giovanni XXIII of Bergamo, Piazza OMS 1, 24127, Bergamo, Italy.
M SalvettiNeurology and Department of Neurosciences, Mental Health and Sensory Organs, Centre for Experimental Neurological Therapies (CENTERS), Sapienza University of Rome, Rome, Italy.
P SolaNeurology Unit, Department of Neuroscience, University of Modena, Nuovo Ospedale Civile S. Agostino Estense, Estense, Italy.
C SolaroNeurology Unit, Department Head and Neck, ASL3 Genovese, Genoa, Italy.
C KlersyBiometry and Statistics Service, IRCCS Fondazione Policlinico S Matteo, Pavia, Italy.
F MarinoCenter for Research in Medical Pharmacology, University of Insubria, Via Ottorino Rossi n. 9, 21100, Varese, VA, Italy.
M ZaffaroniMultiple Sclerosis Center, Gallarate Hospital, Gallarate, Italy.
M CosentinoCenter for Research in Medical Pharmacology, University of Insubria, Via Ottorino Rossi n. 9, 21100, Varese, VA, Italy. marco.cosentino@uninsubria.it.ORCID http://orcid.org/0000-0002-6978-7775

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Though recent progress in multiple sclerosis (MS) treatment is remarkable, numerous unmet needs remain to be addressed often inducing patients to look for complementary and alternative medicines (CAM), especially herbal remedies (HR). HR use, scarcely investigated in MS, may cause adverse reactions (AR) and interfere with conventional treatment. We performed a survey aimed at evaluating use and attitudes towards HR and factor associated to HR use. Other CAM use and attitudes have been investigated as well. Multiple-choice questionnaires were distributed to MS out patients attending 14 Italian referral Centers. Multivariable logistic regression was used to identify HR use determinants. Present/past HR use for either MS or other diseases was reported in 35.6 % of 2419 cases (95 % CI 36.0-40.0 %). CAM use was reported in 42.5 % of cases. Independent predictors of HR use were represented by higher education, geographic area, dissatisfaction with conventional treatment of diseases other than MS and benefit perception from CAM use. Both HR and CAM use were not always disclosed to the healthcare professional. In conclusion, HR and other CAM appear to be popular among MS patients. The involvement of the healthcare professionals appears to be scarce with potential risk of AR or interference with conventional treatments.

Indexed as

AdolescentAdultAgedChildComplementary TherapiesFemaleHealth Knowledge, Attitudes, PracticeHumansItalyLogistic ModelsMaleMiddle AgedMultiple SclerosisMultivariate AnalysisPhytotherapyComplementary alternative medicineHerbal remediesMultiple sclerosisNation-wide surveyQuestionnaireUnmet needs

Identifiers

PMID26895323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.