ArticleSocial science & medicine (1982)2016
Double-jeopardy: The joint impact of neighborhood disadvantage and low social cohesion on cumulative risk of disease among African American men and women in the Jackson Heart Study.
Article in Social science & medicine (1982), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research.International journal of environmental research and public health · 2022Pooled it
- Living in Historically Redlined Neighborhoods and the Cognitive Function of Black and White Adults.Journal of aging and health · 2026Article
- Community-level social capital and postoperative outcomes following intracranial tumor surgery: an exploration of the Social Capital Atlas in neurosurgical oncology.Journal of neuro-oncology · 2025Article
- The association between perceived neighborhood safety and cardiovascular disease risk factors.Psychology, health & medicine · 2025Article
- Neighborhood homicide rate and odds of colorectal adenoma among adult patients seeking colonoscopy.JNCI cancer spectrum · 2024Article
- Social determinants of inflammatory markers linking depression and type 2 diabetes among women: A scoping review.Journal of psychosomatic research · 2024Article
- Cause-Specific Mortality and Racial Differentials in Life Expectancy, Chicago 2018-2019.Journal of racial and ethnic health disparities · 2024Article
- Associations between dimensions of the social environment and cardiometabolic risk factors: Systematic review and meta-analysis.SSM - population health · 2024Review
- Association of Neighborhood Deprivation and Depressive Symptoms With Epigenetic Age Acceleration: Evidence From the Canadian Longitudinal Study on Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Examining the Relationship Between Multilevel Resilience Resources and Cardiovascular Disease Incidence, Overall and by Psychosocial Risks, Among Participants in the Jackson Heart Study, the Multi-Ethnic Study of Atherosclerosis, and the Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study.American journal of epidemiology · 2023Article
- Neighborhood factors and survival to old age: The Jackson Heart Study.Preventive medicine reports · 2023Article
- Impact of Neighborhood on Cardiovascular Health: A Contemporary Narrative Review.Current cardiology reports · 2023Review
- Community Social Capital and Population Health Outcomes.JAMA network open · 2023Article
- Neighborhood socioeconomic status and mortality in the nurses' health study (NHS) and the nurses' health study II (NHSII).Environmental epidemiology (Philadelphia, Pa.) · 2023Article
- Navigating Black Aging: The Biological Consequences of Stress and Depression.The journals of gerontology. Series B, Psychological sciences and social sciences · 2022Article
- Healthcare service utilization for formerly homeless veterans in permanent supportive housing: Do neighborhoods matter?Psychological services · 2022Article
- Advancing health equity through integrated biology and population health research: A community-based sample cortisol feasibility and exploratory study.Comprehensive psychoneuroendocrinology · 2022Article
- Neighborhood Makes or Breaks Active Ageing? Findings from Cross-Sectional Path Analysis.International journal of environmental research and public health · 2022Article
- Pain-related stigma as a social determinant of health in diverse pediatric pain populations.Frontiers in pain research (Lausanne, Switzerland) · 2022Review
- Neighborhood characteristics and ideal cardiovascular health among Black adults: results from the Morehouse-Emory Cardiovascular (MECA) Center for Health Equity.Annals of epidemiology · 2022Article
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5 authors.
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Abstract
objectivesFew studies have examined the joint impact of neighborhood disadvantage and low social cohesion on health. Moreover, no study has considered the joint impact of these factors on a cumulative disease risk profile among a large sample of African American adults. Using data from the Jackson Heart Study, we examined the extent to which social cohesion modifies the relationship between neighborhood disadvantage and cumulative biological risk (CBR)-a measure of accumulated risk across multiple physiological systems.
methodsOur analysis included 4408 African American women and men ages 21-85 residing in the Jackson, MS Metropolitan Area. We measured neighborhood disadvantage using a composite score of socioeconomic indicators from the 2000 US Census and social cohesion was assessed using a 5-item validated scale. Standardized z-scores of biomarkers representing cardiovascular, metabolic, inflammatory, and neuroendocrine systems were combined to create a CBR score. We used two-level linear regression models with random intercepts adjusting for socio-demographic and behavioral covariates in the analysis. A three-way interaction term was included to examine whether the relationship between neighborhood disadvantage and CBR differed by levels of social cohesion and gender.
resultsThe interaction between neighborhood disadvantage, social cohesion and gender was statistically significant (p = 0.05) such that the association between living in a disadvantaged neighborhood and CBR was strongest for men living in neighborhoods with low levels of social cohesion (B = 0.63, SE: 0.32). In gender-specific models, we found a statistically significant interaction between neighborhood disadvantage and social cohesion for men (p = 0.05) but not for women (p = 0.50).
conclusionNeighborhoods characterized by high levels of economic disadvantage and low levels of social cohesion contribute to higher cumulative risk of disease among African American men. This suggests that they may face a unique set of challenges that put them at greater risk in these settings.
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