ArticleJournal of natural medicines2016
Anti-inflammatory and blood stasis activities of essential oil extracted from Artemisia argyi leaf in animals.
Article in Journal of natural medicines, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 70 citations in OpenAlex.
- Shexiang Tongxin Dropping Pill Improves Stable Angina Patients with Phlegm-Heat and Blood-Stasis Syndrome: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.Chinese journal of integrative medicine · 2025Trial
- Analysis of Acupoint Selection and Combination for Gouty Arthritis Treated with Moxibustion Based on Data Mining.Medical acupuncture · 2025Article
- Transcriptome and metabolome analyses revealed the main profiles contributing the mild aroma characteristics ofFrontiers in plant science · 2025Article
- Article
- A review of the research progress on Artemisia argyi Folium: botany, phytochemistry, pharmacological activities, and clinical application.Naunyn-Schmiedeberg's archives of pharmacology · 2024Review
- Procedures to evaluate potential of plants as natural food preservatives: Phytochemical characterization, novel extraction technology, and safety evaluation-A comprehensive review.Food science & nutrition · 2024Review
- Multiplicative Effects of Essential Oils and Other Active Components on Skin Tissue and Skin Cancers.International journal of molecular sciences · 2024Review
- Efficacy of borneol-gypsum in skin regeneration and pain control in toxic epidermal necrolysis: A case report.World journal of clinical cases · 2024Article
- Research progress on the regulation and mechanism of borneol on the blood-brain barrier in pathological states: a narrative review focused on ischemic stroke and cerebral glioma.Translational cancer research · 2023Review
- Antiviral activities of Artemisia vulgaris L. extract against herpes simplex virus.Chinese medicine · 2023Article
- Transcriptome Analysis Reveals the Anti-Tumor Mechanism of Eucalyptol Treatment on Neuroblastoma Cell Line SH-SY5Y.Neurochemical research · 2022Article
- Study on the Regulation of Exogenous Hormones on the Absorption of Elements and the Accumulation of Secondary Metabolites in the Medicinal PlantMetabolites · 2022Article
- Genome sequencing reveals chromosome fusion and extensive expansion of genes related to secondary metabolism in Artemisia argyi.Plant biotechnology journal · 2022Article
- An Extract ofAnimals : an open access journal from MDPI · 2022Article
- Moxibustion alleviates chronic heart failure by regulating mitochondrial dynamics and inhibiting autophagy.Experimental and therapeutic medicine · 2022Article
- Artemisia argyi extract alleviates inflammation in a DSS-induced colitis mouse model and enhances immunomodulatory effects in lymphoid tissues.BMC complementary medicine and therapies · 2022Article
- Moxa Wool in Different Purities and Different Growing Years Measured by Terahertz Spectroscopy.Plant phenomics (Washington, D.C.) · 2022Article
- Study on the Multitarget Mechanism and Active Compounds of Essential Oil fromEvidence-based complementary and alternative medicine : eCAM · 2022Article
- Effects of essential oil extracted fromFrontiers in nutrition · 2022Article
- Anticoccidial activity of natural plants extracts mixture againstFrontiers in veterinary science · 2022Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artemisia argyi leaf is a well-known species in traditional Chinese medicine. However, the anti-inflammatory and activating blood stasis activities of its essential oil (AAEO) have not been explored in vivo. The present study measured the contents of three chemical components by gas chromatography (GC). The anti-acute inflammatory effects of AAEO were investigated in dimethyl benzene, glacial acetic acid and carrageenan-induced animals through skin administration or by oral gavage, respectively. The effects of AAEO on haemorheology were studied in a rat acute blood stasis model. The contents of eucalyptol, camphor and borneol in AAEO were 254.4, 51.6 and 58.7 mg/g, respectively. All dosages of AAEO by skin administration significantly decreased the swelling in dimethyl benzene-induced ear oedema and carrageenan-induced paw oedema, and reduced the permeability in glacial acetic acid-induced abdominal blood capillary (p < 0.01). Meanwhile, haemorheology indexes such as whole blood viscosity and the erythrocyte aggregation index significantly decreased only in the high dosage group. In addition, the effects of AAEO by oral gavage were weaker than skin administration at the medium dose in the experiments. It suggests that AAEO has better absorption bioavailability and pharmacological effects through skin administration due to the better skin permeability of essential oil than gastrointestinal absorption.
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