Evidence map›Paper›PMID 26894161›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Effect of Topical Application of the Cream Containing Magnesium 2% on Treatment of Diaper Dermatitis and Diaper Rash in Children A Clinical Trial Study.

Seyyed Mohammad-Kazem Nourbakhsh, Hojjatollah Rouhi-Boroujeni, Maryam Kheiri, Mahmoud Mobasheri, Majid Shirani, Saeedeh Ahrani, Javad Karami, Zahra Keivani Hafshejani

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427760 (Effect of Using Oxygen on the Diaper Dermatitis in Infants), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05427760 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Using Oxygen on the Diaper Dermatitis in Infants

TypeinterventionalSponsorIstanbul University - CerrahpasaRan2022 to 2023Enrolled103ConditionsDiaper Rash, Diaper DermatitisArmsOxygen
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Seyyed Mohammad-Kazem NourbakhshAssistant Professor, Department of Pediatrics, Tehran University of Medical Sciences , Shahrekord, Iran .
Hojjatollah Rouhi-BoroujeniStudent, Student Research Committee, Department of Medicinal Plants, Medical Plants Research Center, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Maryam KheiriCommunity Medicine, Department of Biostatistics, Isfahan University of Medical Sciences , Isfahan, Iran .
Mahmoud MobasheriAssociate Professor, Department of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Majid ShiraniAssistant Professor, Department of Surgery, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Saeedeh AhraniPediatrician, Department of Pediatrics, Sabzevar University of Medical Sciences , Sabzevar, Iran .
Javad KaramiGeneral Practitioner, Department of Pediatrics, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Zahra Keivani HafshejaniResearch Expert, Department of Nursing, Research and Technology Division, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Shahrekord University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiaper dermatitis is referred to the inflammation in outer layers of the skin in the perineal area, lower abdomen, and inner thighs. The lesions are maculopapular and usually itchy, which could cause bacterial or candida infection, and predispose the infants to penis or vaginal and urinary infection and lead to discomfort, irritability, and restlessness. The drugs which have been so far administered for this disease (topical steroids) cause special complications for the sensitive skin in this area. Magnesium (Mg) is known for its anti-inflammatory and wound-healing properties.

aimThe aim of the present study was to study the effect of the cream containing Mg 2% on treatment of diaper dermatitis and diaper rash in children. MATERIALS AND

methodsIn this clinical trial study, 64 children aged less than two years old with diaper dermatitis referring Paediatric Ward of Hajar Hospital were randomly assigned to two groups of 32. Group one was treated with the combined cream Mg 2% and Calendula and group two with Calendula cream alone. The duration of recovery was compared between the two groups.

resultsThe duration of recovery was significantly lower in the intervention group than the control group (p-value<0.001), but there was no significant difference in the lesions size and diapers' number between the two groups.

conclusionBased on the finding of this study, Mg is effective on treatment of diaper dermatitis and could be used for treating diaper dermatitis and other types of dermatitis.

Indexed as

CalendulaInflammationOintment

Identifiers

PMID26894161
PMCPMC4740689
OpenAlexW2444495763

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.