Evidence map›Paper›PMID 26894142›Full record

ArticleJournal of clinical and diagnostic research : JCDR2016

Age-Related Normogram for Ovarian Antral Follicle Count in Women with Polycystic Ovary Syndrome and Comparison with Age Matched Controls Using Magnetic Resonance Imaging.

Senthil Kumar Aiyappan, Bulabai Karpagam, V Vadanika, Prem Kumar Chidambaram, S Vinayagam, K C Saravanan

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Senthil Kumar AiyappanAssociate Professor, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
Bulabai KarpagamAssociate Professor, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
V VadanikaJunior Resident, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
Prem Kumar ChidambaramAssistant Professor, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
S VinayagamProfessor, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
K C SaravananProfessor, Department of Radiodiagnosis, SRM Medical College Hospital and Research Centre , SRM Nagar, Potheri, Kattankulathur, Kancheepuram, Tamilnadu, India .
SRM Institute of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntral Follicle count (AFC) is a reliable marker for ovarian reserve. Previous studies have used transvaginal ultrasound for estimation of AFC, however we used magnetic resonance imaging (MRI) for estimation of AFC and for creating an age-related normogram in patients with polycystic ovary syndrome (PCOS) and compared it with normal patients.

aimThe aim of this study is to create an age related normogram for AFC in women with PCOS and to compare that with women without polycystic ovarian syndrome using MRI. MATERIALS AND

methodsA total of 1500 women were examined, out of which 400 fitted the criteria for PCOS. They all underwent MRI study and similar age matched women without PCOS also underwent MRI examination. Normogram for AFC were obtained using LMS software and a percentile chart was obtained.

resultsNormogram for AFC in PCOS women showed decline in number of AFC as the age progresses and the decline was linear. The normogram for AFC was compared with equal number of patients without PCOS and they also showed decline in AFC as the age progresses, however the decline was exponential and faster.

conclusionAge related normogram for AFC is widely used and considered as best clinical predictor for ovarian response in assisted reproductive technology. Knowledge of ovarian reserve is important in PCOS and non-PCOS females as PCOS patients are at risk for ovarian hyperstimulation syndrome during gonadotrophin theraphy. MRI is an equally effective and in some times better alternative to transvaginal ultrasound as it has got its own advantages.

Indexed as

Assisted reproductive technologyOvarian hyperstimulation syndromeOvarian reserveTransvaginal ultrasound

Identifiers

PMID26894142
PMCPMC4740670
OpenAlexW2399395344

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.