Evidence map›Paper›PMID 26893919›Full record

ArticleClinical hypertension2015

Diurnal variation of flow-mediated dilatation in healthy humans.

Yong Cheol Kim, Kyeong Ho Yun, Sun Ho Woo, Young Hoon Jeong, Jae Hong Lim, Kyo Bum Hwang, Jin Woo Jeong, Mi Rim Lee, Jeong Mi Lee, Sang Jae Rhee and 3 more

Abstract read
In one paragraph

Article in Clinical hypertension, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yong Cheol KimDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Kyeong Ho YunDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea ; Regional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Sun Ho WooDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Young Hoon JeongDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Jae Hong LimDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Kyo Bum HwangDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Jin Woo JeongDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Mi Rim LeeRegional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Jeong Mi LeeDepartment of Public Health, Wonkwang University Graduate School, Iksan, Korea.
Sang Jae RheeDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea ; Regional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Nam-Ho KimDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea ; Regional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Seok Kyu OhDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea ; Regional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.
Jin-Won JeongDepartments of Cardiovascular Medicine, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea ; Regional Cardiocerebrovascular Center, Wonkwang University School of Medicine and Hospital, 895 Muwang-ro, Iksan, Jeonbuk 570-711 Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe measurement of flow-mediated dilatation (FMD) via ultrasound has been established as a reliable non-invasive measurement of endothelial function. However, the guidelines mention nothing regarding diurnal variation of FMD. Thus, we investigated the FMD in healthy people and diurnal variation of FMD.

methodsTwenty-five apparently healthy persons participated in this study. All participants had no history of cardiovascular diseases, hypertension, or diabetes and used any medication. For each volunteer, the measurements were repeated in the morning and afternoon on two different days. We checked capillary blood glucose, total cholesterol, triglyceride, high-density lipoprotein (HDL), and low-density lipoprotein (LDL)-cholesterol.

resultsThe average of FMD measurements was 8.45% ± 2.39%. The mean values of systolic and diastolic blood pressure, heart rate, lipid profiles, and glucose levels were similar between the morning and afternoon measurements after 9-h fasting. There was no significant difference of FMD measurements between the morning and afternoon (8.32% ± 2.27% and 8.58% ± 2.56%, p = 0.329). Moreover, there was significant correlation between FMD in the morning and afternoon (r = 0.856, p < 0.001).

conclusionsOur study shows measurement of FMD was 8.45% in healthy Koreans. Also, there was no significant difference of FMD measurements between the morning and afternoon.

Indexed as

Circadian variationDiurnal variationFlow-mediated dilatation

Identifiers

PMID26893919
PMCPMC4750800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.