ArticleSAGE open medicine2016
Profiling of Alzheimer's disease patients in Puerto Rico: A comparison of two distinct socioeconomic areas.
Article in SAGE open medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Educational attainment is associated with reduced functional decline in Puerto Ricans with elevated pTau181.Journal of Alzheimer's disease : JAD · 2026Article
- The influence of socioeconomic factors and apolipoprotein ε genotype on cognitive outcomes in a multi-ethnic sample living with HCV and HIV.International journal of STD & AIDS · 2025Article
- Impact of Childhood Adversity on Late-Life Cognition in Older Puerto Rican Adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Alzheimer's disease and Alzheimer's disease-related dementias in Hispanics: Identifying influential factors and supporting caregivers.Ageing research reviews · 2024Review
- Revisiting social MPE: an integration of molecular pathological epidemiology and social science in the new era of precision medicine.Expert review of molecular diagnostics · 2021Article
- Nurturing interest in science and understanding the role of a scientist by teaching younger students how to apply scientific thinking during daily activities.Advances in physiology education · 2018Article
- Socio-demographic and cardiovascular disease risk factors associated with dementia: Results of a cross-sectional study from Lebanon.Preventive medicine reports · 2018Article
- Development of Regional Disparities in Alzheimer's Disease Mortality in the Slovak Republic from 1996 to 2015.International journal of Alzheimer's disease · 2018Article
- Alzheimer's Disease in the Latino Community: Intersection of Genetics and Social Determinants of Health.Journal of Alzheimer's disease : JAD · 2017Review
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Authors and funding
5 authors.
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Abstract
objectiveThe Latino/Hispanic community in the United States is at higher risk of developing Alzheimer's disease than other ethnic groups. Specifically, Caribbean Hispanics showed a more severe Alzheimer's disease symptomatology than any other ethnic group. In a previous study, we demonstrated that the mortality rate associated with Alzheimer's disease in Puerto Rico is higher than that reported in the United States. Moreover, the mortality rate associated with Alzheimer's disease was higher among Puerto Rican living in Puerto Rico than those in the mainland United States. There is also a differential geographical distribution of mortality rate associated with Alzheimer's disease in Puerto Rico, which may be associated with differential socioeconomic status and/or access to healthcare. However, there is no information regarding the clinical profile of Alzheimer's disease patients in Puerto Rico.
methodsHere, we present the results of a retrospective study directed to profile Alzheimer's disease patients clustered into two groups based on areas previously determined with low (Metro Region) and high (Northwest-Central Region) mortality rate associated with Alzheimer's disease in Puerto Rico.
resultsSignificant difference in the age-at-diagnosis and years of education was found among patients within the two studied regions. Despite these differences, both regions showed comparable levels of initial and last Mini Mental State Examination scores and rate of cognitive decline. Significant difference was also observed in the occurance of co-morbidities associated with Alzheimer's disease.
conclusionsThe differential profile of Alzheimer's disease patients correlated with differences in socioeconomic status between these two regions, suggesting that covariant associated with social status may contribute to increased risk of developing Alzheimer's disease. Further studies should be conducted to determine the role of socioeconomic factors and healthy living practices as risk factors for Alzheimer's disease.
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