ArticleNeuropsychiatric disease and treatment2016
Depot-medication compliance for patients with psychotic disorders: the importance of illness insight and treatment motivation.
Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- The effect of financial incentives on patients' motivation for treatment: results of "Money for Medication," a randomised controlled trial.BMC psychiatry · 2018Trial
- Financial incentives and long-acting injectable antipsychotics engagement: community mental health professionals' perspectives.BMC psychiatry · 2025Article
- Antipsychotic medication non-adherence and factors associated among patients with schizophrenia in eastern Ethiopia.BMC psychiatry · 2024Article
- Computational psychiatry approach to stigma subtyping in patients with mental disorders: explicit and implicit internalized stigma.Consortium psychiatricum · 2023Article
- Insight in obsessive-compulsive disorder: conception, clinical characteristics, neuroimaging, and treatment.Psychoradiology · 2023Review
- Factors influencing medication adherence among patients with severe mental disorders from the perspective of mental health professionals.BMC psychiatry · 2022Article
- Revisiting Drug Compliance: The Need for a Holistic Approach in the Treatment of Severe Mental Disorders.Consortium psychiatricum · 2021Article
- Validation of the MUSIC Model of Motivation Inventory for use with cognitive training for schizophrenia spectrum disorders: A multinational study.Schizophrenia research · 2019Article
- Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2018Article
- Patterns of Prescription of Psychotropic Medications and Their Adherence among Patients with Schizophrenia in Two Psychiatric Hospitals in Accra, Ghana: A Cross-Sectional Survey.Psychiatry journal · 2018Article
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5 authors.
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Abstract
backgroundNoncompliance is a major problem for patients with a psychotic disorder. Two important risk factors for noncompliance that have a severe negative impact on treatment outcomes are impaired illness insight and lack of motivation. Our cross-sectional study explored how they are related to each other and their compliance with depot medication.
methodsInterviews were conducted in 169 outpatients with a psychotic disorder taking depot medication. Four patient groups were defined based on low or high illness insight and on low or high motivation. The associations between depot-medication compliance, motivation, and insight were illustrated using generalized linear models.
resultsGeneralized linear model showed a significant interaction effect between motivation and insight. Patients with poor insight and high motivation for treatment were more compliant (94%) (95% confidence interval [CI]: 1.821, 3.489) with their depot medication than patients with poor insight and low motivation (61%) (95% CI: 0.288, 0.615). Patients with both insight and high motivation for treatment were less compliant (73%) (95% CI: 0.719, 1.315) than those with poor insight and high motivation.
conclusionMotivation for treatment was more strongly associated with depot-medication compliance than with illness insight. Being motivated to take medication, whether to get better or for other reasons, may be a more important factor than having illness insight in terms of improving depot-medication compliance. Possible implications for clinical practice are discussed.
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