ReviewClinical interventions in aging2016
Optimal breast cancer screening strategies for older women: current perspectives.
Review in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Mindfulness-Based Stress Reduction on breast cancer symptoms: systematic review and meta-analysis.Einstein (Sao Paulo, Brazil) · 2018Pooled it
- The effect of the combination therapy with chlorophyllin, a glutathione transferase P1-1 inhibitor, and docetaxel on triple-negative breast cancer invasion and metastasis in vivo/in vitro.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Article
- Comparative Analysis and Future Prospects of Human Epidermal Growth Factor Receptor 2 (HER2) and Trophoblast Cell-Surface Antigen 2 (Trop-2) Targeted Antibody-Drug Conjugates in Breast Cancer Treatment.Breast cancer (Dove Medical Press) · 2024Review
- Clinician and patient perspectives on screening mammography among women age 75 and older: A pilot study of a novel decision aid.PEC innovation · 2023Article
- Epidemiology of Breast Cancer Mortality in Kazakhstan, trends and Geographic Distribution.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Breast cancer screening and diagnosis in older adults women in Brazil: why it is time to reconsider the recommendations.Frontiers in public health · 2023Article
- The ability of digital breast tomosynthesis to reduce additional examinations in older women.Frontiers in medicine · 2023Article
- Breast biopsy patterns and findings among older women undergoing screening mammography: The role of age and comorbidity.Journal of geriatric oncology · 2022Article
- Adjuvant Treatment of Elderly Breast Cancer Patients: Offer the Best Chances of Cure.Breast care (Basel, Switzerland) · 2022Review
- Breast Cancer in the Elderly: An Observational Study Investigating Compliance of Screening Mammography in an Underserved Community.World journal of oncology · 2021Article
- A mixed-methods study of multi-level factors influencing mammography overuse among an older ethnically diverse screening population: implications for de-implementation.Implementation science communications · 2021Article
- New Advances in the Research of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.International journal of molecular sciences · 2021Review
- Association of Breast Density With Breast Cancer Risk Among Women Aged 65 Years or Older by Age Group and Body Mass Index.JAMA network open · 2021Article
- Mammography use and breast cancer incidence among older U.S. women.Breast cancer research and treatment · 2021Article
- Screening Mammography Outcomes: Risk of Breast Cancer and Mortality by Comorbidity Score and Age.Journal of the National Cancer Institute · 2020Article
- Prognostic Value and Potential Regulatory Mechanism of Alternative Splicing in Geriatric Breast Cancer.Genes · 2020Article
- Cancer statistics for adults aged 85 years and older, 2019.CA: a cancer journal for clinicians · 2019Article
- Efficacy of punarnavine in restraining organ-specific tumour progression in 4T1-induced murine breast tumour model.Inflammopharmacology · 2019Article
- Change of paradigm in treating elderly with breast cancer: are we undertreating elderly patients?Irish journal of medical science · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Breast cancer is a major cause of cancer-related deaths among older women, aged 65 years or older. Screening mammography has been shown to be effective in reducing breast cancer mortality in women aged 50-74 years but not among those aged 75 years or older. Given the large heterogeneity in comorbidity status and life expectancy among older women, controversy remains over screening mammography in this population. Diminished life expectancy with aging may decrease the potential screening benefit and increase the risk of harms. In this review, we summarize the evidence on screening mammography utilization, performance, and outcomes and highlight evidence gaps. Optimizing the screening strategy will involve separating older women who will benefit from screening from those who will not benefit by using information on comorbidity status and life expectancy. This review has identified areas related to screening mammography in older women that warrant additional research, including the need to evaluate emerging screening technologies, such as tomosynthesis among older women and precision cancer screening. In the absence of randomized controlled trials, the benefits and harms of continued screening mammography in older women need to be estimated using both population-based cohort data and simulation models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.