Evidence map›Paper›PMID 26893297›Full record

ArticleAmerican journal of epidemiology2016

Mechanistic Models of Infectious Disease and Their Impact on Public Health.

Justin Lessler, Derek A T Cummings

Abstract readHistorical Article
In one paragraph

Article in American journal of epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Protein Decoys, Alcohol, and Energy Intake: Testing a Mechanistic-Ecological Model.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Review
  5. Article
  6. Toward AI foundation models for epidemics: Promise, challenges, and paths forward.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Higher-order Interaction Matters: Modeling Epidemics via Dynamic Hypergraph Neural Networks.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2026
    Article
  8. Article
  9. Article
  10. Synthesis estimators for transportability with positivity violations by a continuous covariate.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2025
    Article
  11. Modeling zoonotic and vector-borne viruses.Current opinion in virology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Justin Lessler
Derek A T Cummings

Funding

Training, Outreach & Diversity ComponentU54GM088491 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAKOSKI, JOAN M · 2009 to 2018
$16.7M
NIGMS NIH HHS U54 GM088491
6 · The paper itself

Abstract

From the 1930s through the 1940s, Lowell Reed and Wade Hampton Frost used mathematical models and mechanical epidemic simulators as research tools and to teach epidemic theory to students at the Johns Hopkins Bloomberg School of Public Health (then the School of Hygiene and Public Health). Since that time, modeling has become an integral part of epidemiology and public health. Models have been used for explanatory and inferential purposes, as well as in planning and implementing public health responses. In this article, we review a selection of developments in the history of modeling of infectious disease dynamics over the past 100 years. We also identify trends in model development and use and speculate as to the future use of models in infectious disease dynamics.

Indexed as

Epidemiologic MethodsModels, TheoreticalCommunicable DiseasesEpidemicsEpidemiologyHistory, 20th CenturyHistory, 21st CenturyHumansMarylandSchools, Public HealthUniversitiesinfectious diseasemathematical modelingpublic health policy

Identifiers

PMID26893297
PMCPMC5006438

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.