Evidence map›Paper›PMID 26893258›Full record

ReviewThe Journal of physiology2016

Exercise-induced oxidative stress: past, present and future.

Scott K Powers, Zsolt Radak, Li Li Ji

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 168 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
168citing papers in PubMed, 7 pooled it
28.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

168 citing papers in PubMed, 7 syntheses or guidelines pooled it, 323 citations in OpenAlex.

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  4. Effect of Tai Chi on Markers of Oxidative Stress: Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2021
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  12. Chronic βThe Journal of physiology · 2018
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108 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Scott K PowersDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, 32608, USA. spowers@hhp.ufl.edu.
Zsolt RadakResearch Institute of Sport Science, University of Physical Education, Budapest, Hungary.
Li Li JiSchool of Kinesiology, University of Minnesota, 111 Cooke Hall, 1900 University Avenue, Minneapolis, MN, 55455, USA.
University of Florida · USUniversity of Minnesota · USUniversity of Physical Education · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The existence of free radicals in living cells was first reported in 1954 and this important finding helped launch the field of free radical biology. However, the discovery that muscular exercise is associated with increased biomarkers of oxidative stress did not occur until 1978. Following the initial report that exercise promotes oxidative stress in humans, many studies have confirmed that prolonged or short-duration high intensity exercise results in increased radical production in active skeletal muscles resulting in the formation of oxidized lipids and proteins in the working muscles. Since these early descriptive studies, the investigation of radicals and redox biology related to exercise and skeletal muscle has grown as a discipline and the importance of this research in the biomedical sciences is widely recognized. This review will briefly summarize the history of research in exercise-induced oxidative stress and will discuss the major paradigm shifts that the field has undergone and continues to experience. We conclude with a discussion of future directions in the hope of stimulating additional research in this important field.

Indexed as

AnimalsExerciseHumansMuscle ContractionMuscle, SkeletalOxidative StressReactive Oxygen SpeciesReactive Oxygen Species

Identifiers

PMID26893258
PMCPMC5023699
OpenAlexW2280104967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.