ArticleCirculation research2016
Atherosclerosis: Successes, Surprises, and Future Challenges.
Registry-linked trialAbstract readEditorial
In one paragraph
Article in Circulation research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06604117 (A Prospective, Open-label Study Evaluating the Effects of Probucol Combined with Statins on Atherosclerotic Characteristics and Prognosis in Patients with Ischemic Stroke), which is not on this map. Cited by 165 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Prospective, Open-label Study Evaluating the Effects of Probucol Combined with Statins on Atherosclerotic Characteristics and Prognosis in Patients with Ischemic Stroke
PMID 35583875PMID 35508321PMID 34487721PMID 34024117PMID 33883728PMID 33867420PMID 32336234PMID 1435295PMID 21747278PMID 35143758PMID 29115480PMID 21852751other papers from this trial
Open the trial in the graphWho cites it
165 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exploring global research trends in Chinese medicine for atherosclerosis: a bibliometric study 2012-2023.Frontiers in cardiovascular medicine · 2024Pooled it
- Differences in the cargos and functions of exosomes derived from six cardiac cell types: a systematic review.Stem cell research & therapy · 2019Pooled it
- Endoluminal Catheter Pulsed Field Ablation for the Treatment of Atherosclerotic Vascular Disease.Annals of biomedical engineering · 2026Article
- Heparanase gene deficiency suppresses atherosclerosis progression and enhances plaque stability in apolipoprotein E gene knockout mice with diabetes.Clinical science (London, England : 1979) · 2026Article
- Lentinan Attenuates Experimental Atherosclerosis by Regulating Macrophage HCK/GUSB Expression and Amino Acid Metabolic Remodeling.Cardiovascular drugs and therapy · 2026Article
- From copper transport to cuproptosis: emerging therapeutic targets in cardiovascular disease.Molecular and cellular biochemistry · 2026Review
- Targeting the NLRP3 Inflammasome in Atherosclerosis: A Review of Natural Products and Their Molecular Mechanisms.International journal of molecular sciences · 2026Review
- New Advances in the Mechanisms and Therapeutic Strategies of Gut Microbiota in Regulating Glycolipid Metabolism to Combat Atherosclerosis.Journal of cardiovascular translational research · 2026Review
- A fibroblast-like endothelial cell state promotes atherosclerosis via C/EBPβ-activated TGF-β signaling.The EMBO journal · 2026Article
- Article
- miR-567 indicates atherosclerosis development and regulates inflammation, phenotype switch, proliferation, and migration of platelet-derived growth factor (PDGF)-BB-induced vascular smooth muscle cells (VSMCs) via CSF1R.Journal of molecular histology · 2026Article
- Article
- Pathological mechanisms and research progress of multilevel intervention therapy for coronary heart disease.Frontiers in immunology · 2026Review
- Review
- NHE1 in macrophages promotes octanal/Olfr2-induced atherosclerosis via calcium-dependent ROS and NLRP3 inflammasome activation.Scientific reports · 2025Article
- Decoding the Kruppel-like Transcription Factors in Atherosclerosis: Insight from Molecular and Translational Perspectives.International journal of molecular sciences · 2025Review
- Nonlinear Association Between Atherogenic Index of Plasma and Unstable Carotid Plaque: A Single-Center Retrospective Study.Journal of cardiovascular development and disease · 2025Article
- Infection-Related Hospitalization and Incident Heart Failure in MarketScan: A Case-Crossover Study.Journal of the American Heart Association · 2025Article
- Identification and validation of mitochondrial endoplasmic reticulum membrane-related genes in atherosclerosis.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Article
- Hypercholesterolemia Duration and Brain Area Determine Inflammatory Response Intensity and Apoptotic Mediator Activation in Apo ECellular and molecular neurobiology · 2025Article
105 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Peter LibbyFrom the Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (P.L.); Department of Medicine, Division of Metabolism, Endocrinology and Nutrition (K.E.B.), and Department of Pathology (K.E.B.), UW Diabetes Institute, University of Washington, Seattle; and Division of Molecular Medicine, Department of Medicine, Columbia University, New York (A.R.T.). plibby@rics.bwh.harvard.edu.
Karin E BornfeldtFrom the Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (P.L.); Department of Medicine, Division of Metabolism, Endocrinology and Nutrition (K.E.B.), and Department of Pathology (K.E.B.), UW Diabetes Institute, University of Washington, Seattle; and Division of Molecular Medicine, Department of Medicine, Columbia University, New York (A.R.T.).
Alan R TallFrom the Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (P.L.); Department of Medicine, Division of Metabolism, Endocrinology and Nutrition (K.E.B.), and Department of Pathology (K.E.B.), UW Diabetes Institute, University of Washington, Seattle; and Division of Molecular Medicine, Department of Medicine, Columbia University, New York (A.R.T.).
Funding
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4MTTC39B in obesity and atherosclerosisP01HL087123 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WANG, NAN · 2007 to 2022
$31.2MRole of Serum Amyloid A in Diabetic Vascular DiseaseP01HL092969 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOLDBERG, IRA J · 2008 to 2019
$23.5MCholesterol efflux, CHIP and inflammasome activationR01HL107653 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALAN richard TALL · 2011 to 2026
$7.7MMolecular Determinants of Arterial Remodeling in AtherogenesisR01HL080472 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI LIBBY, PETER · 2005 to 2018
$5.0MHYPERGLYCEMIA, PROTEIN KINASES AND SMOOTH MUSCLE GROWTHR01HL062887 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E. · 1998 to 2014
$4.7MTTC39B in MetabolismR01HL119830 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI TALL, ALAN RICHARD · 2015 to 2022
$3.5MObesity and Arterial MetabolismR01HL126028 · NHLBI · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E. · 2015 to 2018
$1.7MAPOC3, HDL Function and Cardiovascular Complications of T1DMDP3DK108209 · NIDDK · UNIVERSITY OF WASHINGTON · PI BORNFELDT, KARIN E., HEINECKE, JAY W · 2015 to 2015
$1.6MNHLBI NIH HHS HL080472NHLBI NIH HHS HL087123NHLBI NIH HHS HL107653NHLBI NIH HHS HL119830NHLBI NIH HHS P01 HL087123NHLBI NIH HHS P01 HL092969NHLBI NIH HHS P01HL092969NHLBI NIH HHS R01 HL062887NHLBI NIH HHS R01HL062887NHLBI NIH HHS R01 HL080472NHLBI NIH HHS R01 HL107653NHLBI NIH HHS R01 HL119830NHLBI NIH HHS R01 HL126028NHLBI NIH HHS R01HL126028NIDDK NIH HHS DP3 DK108209NIDDK NIH HHS DP3DK108209NIDDK NIH HHS P30 DK017047NIDDK NIH HHS P30DK017047
Abstract
PubMed holds no abstract for this paper.
Indexed as
AtherosclerosisAnimalsBiomarkersHumansLipidsPrognosisRisk FactorsBiomarkersLipidsatherosclerosisclinical trialEditorialsendothelial cellsepidemiologyleukocytespharmacologysmooth muscle cellsvascular cell biology
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
NCT06604117ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.