ArticleScientific reports2016
OCT-based label-free in vivo lymphangiography within human skin and areola.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Identification and quantification of oral lymphatic vessel networks using optical coherence tomography (OCT).Biomedical optics express · 2026Article
- Enhanced extraction of human interstitial fluid using microneedles and laser-induced fluid recruitment.iScience · 2025Article
- Deep learning-based label-free imaging of lymphatics and aqueous veins in the eye using optical coherence tomography.Scientific reports · 2024Article
- Lymphography method based on time-autocorrelated optical coherence tomography.Biomedical optics express · 2022Article
- Detection and differentiation of semi-transparent materials simulating biological structures using optical coherence tomography: a phantom study.Journal of biomedical optics · 2022Article
- In Vivo Longitudinal Tracking of Lymphangiogenesis and Angiogenesis in Cutaneous Melanoma Mouse Model Using Multifunctional Optical Coherence Tomography.JID innovations : skin science from molecules to population health · 2021Article
- Imaging Motion: A Comprehensive Review of Optical Coherence Tomography Angiography.Advances in experimental medicine and biology · 2021Review
- Attenuation correction assisted automatic segmentation for assessing choroidal thickness and vasculature with swept-source OCT.Biomedical optics express · 2018Article
- Simultaneous measurements of lymphatic vessel contraction, flow and valve dynamics in multiple lymphangions using optical coherence tomography.Journal of biophotonics · 2018Article
- High-speed optical coherence tomography by circular interferometric ranging.Nature photonics · 2018Article
- Repeatability of vessel density measurement in human skin by OCT-based microangiography.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2017Article
- Determination on the Coefficient of Thermal Expansion in High-Power InGaN-based Light-emitting Diodes by Optical Coherence Tomography.Scientific reports · 2017Article
- Article
- Optical coherence tomography based microangiography provides an ability to longitudinally image arteriogenesis in vivo.Journal of neuroscience methods · 2016Article
- Depth-resolved 3D visualization of coronary microvasculature with optical microangiography.Physics in medicine and biology · 2016Article
- Assessment of edema volume in skin upon injury in a mouse ear model with optical coherence tomography.Lasers in medical science · 2016Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Due to the limitations of current imaging techniques, visualization of lymphatic capillaries within tissue in vivo has been challenging. Here, we present a label-free high resolution optical coherence tomography (OCT) based lymphangiography (OLAG) within human skin in vivo. OLAG enables rapid (~seconds) mapping of lymphatic networks, along with blood vessel networks, over 8 mm x 8 mm of human skin and 5 mm x 5 mm of human areola. Moreover, lymphatic system's response to inflammation within human skin is monitored throughout an acne lesion development over 7 days. The demonstrated results promise OLAG as a revolutionary tool in the clinical research and treatment of patients with pathologic conditions such as cancer, diabetes, and autoimmune diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.