Evidence map›Paper›PMID 26892622›Full record

ArticleAIDS research and human retroviruses

Increased Antiretroviral Therapy Use and Virologic Suppression in the Bronx in the Context of Multiple HIV Prevention Strategies.

David B Hanna, Uriel R Felsen, Mindy S Ginsberg, Barry S Zingman, Robert S Beil, Donna C Futterman, Howard D Strickler, Kathryn Anastos

Abstract read
In one paragraph

Article in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Development and Evaluation of a Novel Algorithm to Identify Doxycycline Postexposure Prophylaxis Users at a Large Healthcare System in the Bronx, New York.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
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  6. Article
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  9. Amino-terminal Pro-B-Type Natriuretic Peptide Among Patients Living With Both Human Immunodeficiency Virus and Heart Failure.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  10. Article
  11. Impact of an HIV Care Coordination Program on Durable Viral Suppression.Journal of acquired immune deficiency syndromes (1999) · 2019
    Observational
  12. Article
  13. Article
  14. Article
  15. Article
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  18. Observational
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David B Hanna1 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.
Uriel R Felsen2 Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center , Bronx, New York.
Mindy S Ginsberg1 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.
Barry S Zingman2 Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center , Bronx, New York.
Robert S Beil2 Department of Medicine, Albert Einstein College of Medicine and Montefiore Medical Center , Bronx, New York.
Donna C Futterman3 Department of Pediatrics, Albert Einstein College of Medicine and Montefiore Medical Center , Bronx, New York.
Howard D Strickler1 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.
Kathryn Anastos1 Department of Epidemiology and Population Health, Albert Einstein College of Medicine , Bronx, New York.

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Immunology/Pathology CoreP30AI051519 · NIAID · YESHIVA UNIVERSITY · PI PORCELLI, STEVEN A · 2003 to 2013
$18.6M
ADOLESCENT MEDICINE TRIALS UNITU01HD040499 · NICHD · MONTEFIORE MEDICAL CENTER (BRONX, NY) · PI FUTTERMAN, DONNA · 2001 to 2015
$11.0M
Role of innate immunity in HIV related vascular disease: biomarkers & mechanismsR01HL126543 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAPLAN, ROBERT C · 2014 to 2017
$3.7M
TestED!: Applying Implementation Science to improve an HIV testing strategy for Emergency DepartmentsK23MH106386 · NIMH · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FELSEN, URIEL · 2015 to 2019
$920k
NCATS NIH HHS UL1 TR001073NHLBI NIH HHS R01 HL126543NIAID NIH HHS P30 AI051519NICHD NIH HHS U01 HD040499NIMH NIH HHS K23 MH106386
6 · The paper itself

Abstract

Multiple population-based HIV prevention strategies from national, state, local, and institutional levels have been implemented in the Bronx, which has one of the highest HIV prevalences in the U.S. We examined changes in antiretroviral therapy (ART) use and associated outcomes between 2007 and 2014 among patients seen at one of >20 outpatient clinics affiliated with the largest Bronx HIV care provider. Among eligible HIV-infected patients age ≥13 years, we examined annual trends in ART use, mean HIV RNA level, and virologic suppression (<200 copies/ml) overall and among prespecified subgroups. In a subset with suppressed HIV RNA at the end of each year, we determined the percentage whose levels remained suppressed within the next year. Regression models assessed disparities in outcomes. Among 7,196 patients (median age 50, 47% Hispanic, 45% black), we identified consistent increases over time in the percent prescribed ART (78% in 2007 to 93% in 2014) and with virologic suppression (58% to 80%), as mean HIV RNA decreased (351 to 73 copies/ml) (all p < .001). Sustained virologic suppression improved markedly beginning in 2011, coinciding with local test-and-treat initiatives and adoption of expanded treatment guidelines. While disparities among population groups were most pronounced for sustained virologic suppression, those aged 13-24 fared relatively poorly for all outcomes examined (e.g., rate ratio 0.57 for virologic suppression, 95% confidence interval 0.52-0.62, vs. age 65+). Population-wide HIV prevention strategies coincided with improvements in virologic suppression among most population groups. However, more attention is needed to address continued disparities in the HIV care continuum among young people.

Indexed as

Drug UtilizationSustained Virologic ResponseViral LoadAdolescentAdultAgedAged, 80 and overAnti-Retroviral AgentsDisease Transmission, InfectiousFemaleHIV InfectionsHumansMaleMiddle AgedNew York CityRNA, ViralAnti-Retroviral AgentsRNA, Viralantiretroviral therapycommunity viral loadHIV preventionHIV viral loadtest-and-treatyoung adult

Identifiers

PMID26892622
PMCPMC5067794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.