ArticleThe journal of nutrition, health & aging2016
Associations of Low Muscle Mass and the Metabolic Syndrome in Caucasian and Asian Middle-aged and Older Adults.
Article in The journal of nutrition, health & aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Association between Sarcopenia and Metabolic Syndrome in Middle-Aged and Older Non-Obese Adults: A Systematic Review and Meta-Analysis.Nutrients · 2018Pooled it
- Evenly Distributed Protein Intake over 3 Meals Augments Resistance Exercise-Induced Muscle Hypertrophy in Healthy Young Men.The Journal of nutrition · 2020Trial
- Sexual Dimorphism in the Relationship between Body Composition and Insulin Resistance in Older Adults.Current developments in nutrition · 2026Article
- Association between appendicular lean mass-to-body weight ratio and metabolic syndrome in community-dwelling older adults in Taiwan: A cross-sectional study.The Journal of international medical research · 2026Article
- Development of a machine learning model for predicting pre-sarcopenia in adults with abdominal obesity: a cross-sectional study.Journal of endocrinological investigation · 2026Article
- A Systematic Review and Meta-Analysis of Efficacy and Safety of Liraglutide in Patients with Type 2 Diabetes Mellitus.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Ultrasound evaluation of muscles in older patients with metabolıc syndrome.Irish journal of medical science · 2025Article
- Comparison of bioelectrical impedance analysis and dual-energy X-ray absorptiometry for the diagnosis of sarcopenia in the older adults with metabolic syndrome: equipment-specific equation development.Aging clinical and experimental research · 2024Review
- Association between Muscle Mass Index and Neurological Outcomes of Patients with Out-of-Hospital Cardiac Arrest.Life (Basel, Switzerland) · 2024Article
- The association between creatinine to body weight ratio and the risk of progression to diabetes from pre-diabetes: a 5-year cohort study in Chinese adults.BMC endocrine disorders · 2023Article
- A New Approach Using BMI and FMI as Predictors of Cardio-Vascular Risk Factors among Mexican Young Adults.European journal of investigation in health, psychology and education · 2023Article
- Article
- Adherence to the Mediterranean Diet Related to the Health Related and Well-Being Outcomes of European Mature Adults and Elderly, with an Additional Reference to Croatia.International journal of environmental research and public health · 2023Article
- Editorial: Aging, Body Composition, and Cognitive Decline: Shared and Unique Characteristics.The journal of nutrition, health & aging · 2023Article
- Association between creatinine to body weight ratio and all-cause mortality: a cohort study of NHANES.Renal failure · 2023Article
- Sex-specific associations between gut microbiota and skeletal muscle mass in a population-based study.Journal of cachexia, sarcopenia and muscle · 2022Article
- Sarcopenia and mortality risk in community-dwelling Brazilian older adults.Scientific reports · 2022Article
- Association of Absolute and Relative Handgrip Strength with Prevalent Metabolic Syndrome in Adults: Korea National Health and Nutrition Examination Survey 2014-2018.International journal of environmental research and public health · 2022Article
- Relationship Between Protein Intake in Each Traditional Meal and Physical Activity: Cross-sectional Study.JMIR public health and surveillance · 2022Article
- Metabolic syndrome and its association with components of sarcopenia in older community-dwelling Chinese.Journal of biomedical research · 2022Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAge-related declines in skeletal muscle mass may confer significant metabolic consequences for older adults. Associations of low muscle mass and metabolic syndrome (MetS) in Caucasians, and comparisons with associations observed in Asian populations, have not been reported. We examined associations of low muscle mass and metabolic syndrome (MetS) in Asian and Caucasian middle-aged and older men and women using criteria for low muscle mass. DESIGN, SETTING AND
participantsTwo population-based studies of Australian (Tasmanian Older Adult Cohort Study; TASOAC; N=1005) and Korean (Korean Sarcopenic Obesity Study; KSOS; N=376) community-dwelling adults, mean age 62 and 58 years, respectively. MEASUREMENTS: Appendicular lean mass (aLM) determined by dual-energy X-ray absorptiometry and normalised to height squared (aLM/Ht2), weight (aLM/Wt) or body mass index (aLM/BMI). Participants in the lowest sex-specific 20% for aLM measures were defined as having low muscle mass. MetS was defined according to National Cholesterol Education Program Adult Treatment Panel III criteria.
resultsAlthough Australians demonstrated generally unfavourable anthropometric and metabolic characteristics compared to Koreans, prevalence of MetS was similar (29.5% in Australians and 31.4% in Koreans, respectively). Low aLM/Ht2 was associated with significantly reduced likelihood of MetS in both Australians (OR: 0.30, 95% CI 0.19 - 0.46) and Koreans (OR: 0.31, 95% CI 0.16 - 0.62). Conversely, low aLM/BMI was associated with increased odds for MetS in Australians (OR: 1.78, 95% CI 1.12 - 2.84), but not Koreans (OR: 1.33, 95% CI = 0.67 - 2.64).
conclusionLow aLM/BMI is associated with significantly increased likelihood of MetS in Australian adults, but not Koreans, suggesting potential differences in effects of low muscle mass relative to body mass on cardiometabolic health in Caucasian and Asian middle-aged and older adults. Low muscle mass relative to height is associated with reduced likelihood of MetS in both populations.
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