Evidence map›Paper›PMID 26892420›Full record

ReviewJournal of the American College of Cardiology2016

Diagnostic Strategies for the Evaluation of Chest Pain: Clinical Implications From SCOT-HEART and PROMISE.

Christopher B Fordyce, David E Newby, Pamela S Douglas

Abstract readReview
In one paragraph

Review in Journal of the American College of Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  15. Invasive Coronary Angiography after Chest Pain Presentations to Emergency Departments.International journal of environmental research and public health · 2020
    Article
  16. Article
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  18. All Together Now: Synthesizing Evidence-Based Protocols to Simplify and Expedite Emergency Department Evaluation of Low-Risk Patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christopher B FordyceDuke Clinical Research Institute, Durham, North Carolina. Electronic address: christopher.fordyce@duke.edu.
David E NewbyBritish Heart Foundation/University of Edinburgh Centre for Cardiovascular Science, Edinburgh, United Kingdom.
Pamela S DouglasDuke Clinical Research Institute, Durham, North Carolina.

Funding

PROMISE Trial: Clinical Coordinating CenterR01HL098237 · NHLBI · DUKE UNIVERSITY · PI DOUGLAS, PAMELA SUSAN · 2009 to 2014
$27.3M
PROMISE Trial: SDCCR01HL098236 · NHLBI · DUKE UNIVERSITY · PI LEE, KERRY L · 2009 to 2014
$5.0M
Cardiac MR and CT ResearchT32HL076136 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NEILAN, TOMAS G · 2004 to 2019
$4.9M
PROMISE Trial: Dx CoreR01HL098305 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HOFFMANN, UDO · 2009 to 2014
$3.5M
Chief Scientist Office CZH/4/588Medical Research Council G0701127NHLBI NIH HHS R01 HL098236NHLBI NIH HHS R01 HL098237NHLBI NIH HHS R01 HL098305NHLBI NIH HHS T32 HL076136
6 · The paper itself

Abstract

SCOT-HEART (Scottish COmputed Tomography of the HEART) and PROMISE (PROspective Multicenter Imaging Study for Evaluation of chest pain) represent the 2 largest and most comprehensive cardiovascular imaging outcome trials in patients with stable chest pain and provide significant insights into patient diagnosis, management, and outcomes. These trials are particularly timely, given the well-recognized knowledge gaps and widespread use of noninvasive imaging. The overall goal of this review is to distill the data generated from these 2 pivotal trials to better inform the practicing clinician in the selection of noninvasive testing for stable chest pain. Similarities and differences between SCOT-HEART and PROMISE are highlighted, and clinical and practical implications are discussed. Both trials show that coronary computed tomography angiography should have a greater role in the diagnostic pathway of patients with stable chest pain.

Indexed as

Practice Guidelines as TopicCardiac Imaging TechniquesChest PainCoronary AngiographyCoronary Artery DiseaseDiagnosis, DifferentialElectrocardiographyExercise TestHumansTomography, Emission-Computed, Single-PhotonTomography, X-Ray Computedangina pectoriscoronary artery diseasenoninvasive cardiac imagingpatient selection

Identifiers

PMID26892420
PMCPMC4771619

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.