Evidence map›Paper›PMID 26892001›Full record

Trial reportTrials2016

Virtual reality cue exposure for the relapse prevention of tobacco consumption: a study protocol for a randomized controlled trial.

Camille Giovancarli, Eric Malbos, Karine Baumstarck, Nathalie Parola, Marie-Florence Pélissier, Christophe Lançon, Pascal Auquier, Laurent Boyer

2 registry-linked trialsOpen access · goldAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 5 pooled it
3.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02205060 nacompletednot on this map

Interventionnal and Randomized Study Measuring Virtual Reality Cue Exposure for the Relapse Prevention of Tobacco Consumption Versus Cognitive and Behavioral Approaches Therapy

TypeinterventionalSponsorAssistance Publique Hopitaux De MarseilleRan2014 to 2023Enrolled100ConditionsChronic TabagismArmsvirtual reality exposure treatment, cognitive and behavioral approaches therapy
NCT07013084 nacompletednot on this mapstarted 2020, after this paper: background citation

Study on the Effect of Digital Smoking Cessation Education Intervention on Outpatients

TypeinterventionalSponsorNational Taiwan Normal UniversityRan2020 to 2023Enrolled100ConditionsSmoking CessationArms3D VR smoking cessation program
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Relapse prevention interventions for smoking cessation.The Cochrane database of systematic reviews · 2019
    Pooled it
  5. Pooled it
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Camille GiovancarliDepartment of Psychiatry, La Conception University Hospital, 13005, Marseille, France. camille.giovancarli@ap-hm.fr.
Eric MalbosDepartment of Psychiatry, La Conception University Hospital, 13005, Marseille, France. eric.malbos@ap-hm.fr.
Karine BaumstarckAix-Marseille University, EA 3279 - Public Health, Chronic Diseases and Quality of Life - Research Unit, 13005, Marseille, France. karine.baumstarck@univ-amu.fr.
Nathalie ParolaDepartment of Psychiatry, La Conception University Hospital, 13005, Marseille, France.
Marie-Florence PélissierDepartment of Psychiatry, La Conception University Hospital, 13005, Marseille, France. marie-florence.pelissier@ap-hm.fr.
Christophe LançonDepartment of Psychiatry, La Conception University Hospital, 13005, Marseille, France. christophe.lancon@ap-hm.fr.
Pascal AuquierAix-Marseille University, EA 3279 - Public Health, Chronic Diseases and Quality of Life - Research Unit, 13005, Marseille, France. pascal.auquier@univ-amu.fr.
Laurent BoyerAix-Marseille University, EA 3279 - Public Health, Chronic Diseases and Quality of Life - Research Unit, 13005, Marseille, France. laurent.boyer@ap-hm.fr.
Aix-Marseille Université · FRHôpital de la Conception · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuccessful interventions have been developed for smoking cessation, but the success of smoking relapse prevention interventions has been limited. In particular, cognitive behavioural therapy (CBT) has been hampered by a high relapse rate. Because relapses can be due to the presence of conditions associated with tobacco consumption (such as drinking in bars with friends), virtual reality exposure therapy (VRET) can generate synthetic environments that represent risk situations for the patient in the context of relapse prevention. The primary objective of this study is to evaluate the effectiveness of CBT coupled with VRET, in comparison to CBT alone, in the prevention of smoking relapse. The secondary objectives are to assess the impact of CBT coupled with VRET on anxiety, depression, quality of life, self-esteem and addictive comorbidities (such as alcohol, cannabis, and gambling). A third objective examines the feasibility and acceptability of VR use considering elements such as presence, cybersickness and number of patients who complete the VRET program. METHOD/

designThe present study is a 14-month (2 months of therapy followed by 12 months of follow-up), prospective, comparative, randomized and open clinical trial, involving two parallel groups (CBT coupled with VRET versus CBT alone). The primary outcome is the proportion of individuals with tobacco abstinence at 6 months after the end of the therapy. Abstinence is defined by the total absence of tobacco consumption assessed during a post-test interview and with an apparatus that measures the carbon monoxide levels expired. A total of 60 individuals per group will be included. DISCUSSION: This study is the first to examine the efficacy of CBT coupled with VRET in the prevention of smoking relapse. Because VRET is simple to use and has a low cost, this interactive therapeutic method might be easily implemented in clinical practice if the study confirms its efficacy.

trial registrationClinicalTrials.gov Identifier: NCT02205060 (registered 25 July 2014).

Indexed as

Clinical ProtocolsCuesVirtual Reality Exposure TherapyCognitive Behavioral TherapyData Interpretation, StatisticalHeart RateHumansPatient Outcome AssessmentRecurrenceSample SizeTobacco Use

Identifiers

PMID26892001
PMCPMC4759851
OpenAlexW2281238604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.