ArticleRice (New York, N.Y.)2016
Metabolic and transcriptomic changes induced in host during hypersensitive response mediated resistance in rice against the Asian rice gall midge.
Article in Rice (New York, N.Y.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 26 citations in OpenAlex.
- Bridging germplasm and mechanisms: screening for resistance and decoding defense strategies against rice gall midge (Orseolia oryzae Wood-Mason) in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Combined analysis of metabolome and transcriptome of wheat kernels reveals constitutive defense mechanism against maize weevils.Frontiers in plant science · 2023Article
- Transcriptomics and metabolomics revealed that phosphate improves the cold tolerance of alfalfa.Frontiers in plant science · 2023Article
- Recent advances in proteomics and metabolomics in plants.Molecular horticulture · 2022Review
- Proteomics and Metabolomics Studies on the Biotic Stress Responses of Rice: an Update.Rice (New York, N.Y.) · 2021Review
- Transcriptomic and Metabolomic Analyses Provide Insights Into an Aberrant Tissue of Tea Plant (Frontiers in plant science · 2021Article
- Host Plant Strategies to Combat Against Viruses Effector Proteins.Current genomics · 2020Review
- An Integrated Analysis of the Rice Transcriptome and Metabolome Reveals Root Growth Regulation Mechanisms in Response to Nitrogen Availability.International journal of molecular sciences · 2019Article
- Transcriptome Analysis of Chinese Chestnut (International journal of molecular sciences · 2019Article
- A galling insect activates plant reproductive programs during gall development.Scientific reports · 2019Article
- Map-based cloning and validation of a gall midge resistance gene, Gm8, encoding a proline-rich protein in the rice variety Aganni.Molecular biology reports · 2018Article
- Expression Profile of Defense Genes in Rice Lines Pyramided with Resistance Genes Against Bacterial Blight, Fungal Blast and Insect Gall Midge.Rice (New York, N.Y.) · 2018Article
- Characterization and Identification of a woody lesion mimic mutant lmd, showing defence response and resistance to Alternaria alternate in birch.Scientific reports · 2017Article
- Lactobacillus paracasei metabolism of rice bran reveals metabolome associated with Salmonella Typhimurium growth reduction.Journal of applied microbiology · 2017Article
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4 authors at 3 institutions in 1 country.
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Abstract
backgroundAn incompatible interaction between rice (Oryza sativa) and the Asian rice gall midge (AGM, Orseolia oryzae Wood-Mason), that is usually manifested through a hypersensitive response (HR), represents an intricate relationship between the resistant host and its avirulent pest. We investigated changes in the transcriptome and metabolome of the host (indica rice variety: RP2068-18-3-5, RP), showing HR when attacked by an avirulent gall midge biotype (GMB1), to deduce molecular and biochemical bases of such a complex interaction. Till now, such an integrated analysis of host transcriptome and metabolome has not been reported for any rice-insect interaction.
resultsTranscript and metabolic profiling data revealed more than 7000 differentially expressed genes and 80 differentially accumulated metabolites, respectively, in the resistant host. Microarray data revealed deregulation of carbon (C) and nitrogen (N) metabolism causing a C/N shift; up-regulation of tetrapyrrole synthesis and down-regulation of chlorophyll synthesis and photosynthesis. Integrated results revealed that genes involved in lipid peroxidation (LPO) were up-regulated and a marker metabolite for LPO (azelaic acid) accumulated during HR. This coincided with a greater accumulation of GABA (neurotransmitter and an insect antifeedant) at the feeding site. Validation of microarray results by semi-quantitative RT-PCR revealed temporal variation in gene expression profiles.
conclusionsThe study revealed extensive reprogramming of the transcriptome and metabolome of RP upon GMB1 infestation leading to an HR that was induced by the generation and release of reactive oxygen species i.e. singlet oxygen and resulted in LPO-mediated cell death. RP thus used HR as a means to limit nutrient supply to the feeding maggots and simultaneously accumulated GABA, strategies that could have led to maggot mortality. The integrated results of transcript and metabolic profiling, for the first time, provided insights into an HR+ type of resistance in rice against gall midge.
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