Evidence map›Paper›PMID 26891840›Full record

Trial reportAIDS and behavior2016

Framing HIV Pre-Exposure Prophylaxis (PrEP) for the General Public: How Inclusive Messaging May Prevent Prejudice from Diminishing Public Support.

Sarah K Calabrese, Kristen Underhill, Valerie A Earnshaw, Nathan B Hansen, Trace S Kershaw, Manya Magnus, Douglas S Krakower, Kenneth H Mayer, Joseph R Betancourt, John F Dovidio

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in AIDS and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Sarah K CalabreseDepartment of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, 135 College Street, Suite 358, New Haven, CT, 06510, USA. sarah.calabrese@yale.edu.
Kristen UnderhillCenter for Interdisciplinary Research on AIDS, Yale University, New Haven, CT, USA.
Valerie A EarnshawCenter for Interdisciplinary Research on AIDS, Yale University, New Haven, CT, USA.
Nathan B HansenCenter for Interdisciplinary Research on AIDS, Yale University, New Haven, CT, USA.
Trace S KershawDepartment of Chronic Disease Epidemiology, Yale School of Public Health, Yale University, 135 College Street, Suite 358, New Haven, CT, 06510, USA.
Manya MagnusDepartment of Epidemiology and Biostatistics, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.
Douglas S KrakowerBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Kenneth H MayerBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Joseph R BetancourtDisparities Solutions Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
John F DovidioCenter for Interdisciplinary Research on AIDS, Yale University, New Haven, CT, USA.
Yale University · USBeth Israel Deaconess Medical Center · USHarvard University · USMassachusetts General Hospital · USMilken Institute · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI ROBERT A. PARKER · 2004 to 2026
$94.4M
Using Coincidence Analysis to Investigate Factors Affecting PrEP Initiation and Continuation in Southern ending the Epidemic CountiesP30MH062294 · NIMH · YALE UNIVERSITY · PI John Edward Pachankis · 2001 to 2026
$48.5M
Mentored Career Development for Child and Family Centered Outcomes ResearchK12HS022986 · AHRQ · BOSTON CHILDREN'S HOSPITAL · PI FINKELSTEIN, JONATHAN A · 2014 to 2018
$3.8M
Optimizing HIV Pre-Exposure Prophylaxis through Shared Decision MakingK23MH098795 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI KRAKOWER, DOUGLAS SCOTT · 2012 to 2016
$873k
PrEP for HIV Prevention in MSM: Mixed-Methods Study of Behavior & Message FramingK01MH093273 · NIMH · YALE UNIVERSITY · PI UNDERHILL, KRISTEN · 2011 to 2015
$873k
Intervention to Promote PrEP Awareness and Equitable Prescription among ProvidersK01MH103080 · NIMH · YALE UNIVERSITY · PI CALABRESE, SARAH K. · 2014 to 2017
$634k
AHRQ HHS K12 HS022986NCATS NIH HHS UL1 TR001863NIAID NIH HHS P30 AI060354NIMHD NIH HHS L60 MD008519NIMH NIH HHS K01 MH093273NIMH NIH HHS K01 MH103080NIMH NIH HHS K23 MH098795NIMH NIH HHS P30 MH062294
6 · The paper itself

Abstract

Strategic framing of public messages about HIV pre-exposure prophylaxis (PrEP) may influence public support for policies and programs affecting access. This survey study examined how public attitudes toward PrEP differed based on the social group PrEP was described as benefiting ("beneficiary") and the moderating effect of prejudice. Members of the general public (n = 154) recruited online were randomly assigned to three beneficiary conditions: general population, gay men, or Black gay men. All participants received identical PrEP background information before completing measures of PrEP attitudes (specifying beneficiary), racism, and heterosexism. Despite anticipating greater PrEP adherence among gay men and Black gay men and perceiving PrEP as especially beneficial to the latter, participants expressed lower support for policies/programs making PrEP affordable for these groups vs. the general population. This disparity in support was stronger among participants reporting greater prejudice. Inclusive framing of PrEP in public discourse may prevent prejudice from undermining implementation efforts.

Indexed as

Pre-Exposure ProphylaxisPrejudicePublic OpinionRacismAdultBlack or African AmericanBlack PeopleHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleHumansMalePerceptionSexual BehaviorSurveys and QuestionnairesBlack/African AmericanFramingHIVMen who have sex with men (MSM)Pre-exposure prophylaxis (PrEP)PrejudicePublic opinion

Identifiers

PMID26891840
PMCPMC4903888
OpenAlexW2275962744

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.