Evidence map›Paper›PMID 26891796›Full record

ArticleBMC medical research methodology2016

Head to head comparison of the propensity score and the high-dimensional propensity score matching methods.

Jason R Guertin, Elham Rahme, Colin R Dormuth, Jacques LeLorier

Full text readComparative Study
In one paragraph

Article in BMC medical research methodology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
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  9. Review
  10. Effectiveness of spironolactone dispensation in reducing weekly alcohol use: a retrospective high-dimensional propensity score-matched cohort study.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  11. Article
  12. Review
  13. Article
  14. The association of beta-blocker use with mortality in elderly patients with congestive heart failure and advanced chronic kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020
    Article
  15. Observational
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason R GuertinDepartment of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, ON, Canada. guertinj@mcmaster.ca.
Elham RahmeResearch Institute of the McGill University Health Centre, Montreal, QC, Canada. elham.rahme@mcgill.ca.
Colin R DormuthDepartment of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada. colin.dormuth@ti.ubc.ca.
Jacques LeLorierPharmacoeconomic and Pharmacoepidemiology unit, Research Center of the Centre hospitalier de l'Université de Montréal, Pavillon S, 850 St-Denis, 3e étage, Montreal, QC, Canada. jacques.le.lorier@sympatico.ca.

Funding

Canadian Institutes of Health Research DSE-111845
6 · The paper itself

Abstract

backgroundComparative performance of the traditional propensity score (PS) and high-dimensional propensity score (hdPS) methods in the adjustment for confounding by indication remains unclear. We aimed to identify which method provided the best adjustment for confounding by indication within the context of the risk of diabetes among patients exposed to moderate versus high potency statins.

methodA cohort of diabetes-free incident statins users was identified from the Quebec's publicly funded medico-administrative database (Full Cohort). We created two matched sub-cohorts by matching one patient initiated on a lower potency to one patient initiated on a high potency either on patients' PS or hdPS. Both methods' performance were compared by means of the absolute standardized differences (ASDD) regarding relevant characteristics and by means of the obtained measures of association.

resultsEight out of the 18 examined characteristics were shown to be unbalanced within the Full Cohort. Although matching on either method achieved balance within all examined characteristic, matching on patients' hdPS created the most balanced sub-cohort. Measures of associations and confidence intervals obtained within the two matched sub-cohorts overlapped.

conclusionAlthough ASDD suggest better matching with hdPS than with PS, measures of association were almost identical when adjusted for either method. Use of the hdPS method in adjusting for confounding by indication within future studies should be recommended due to its ability to identify confounding variables which may be unknown to the investigators.

Indexed as

Propensity ScoreAdultAgedAge FactorsCase-Control StudiesComparative Effectiveness ResearchConfidence IntervalsConfounding Factors, EpidemiologicDatabases, FactualFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasLogistic ModelsMaleMiddle AgedHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID26891796
PMCPMC4759710

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.