Evidence map›Paper›PMID 26891382›Full record

ReviewChannels (Austin, Tex.)2016

Surface dynamics of voltage-gated ion channels.

Martin Heine, Anna Ciuraszkiewicz, Andreas Voigt, Jennifer Heck, Arthur Bikbaev

Abstract readReview
In one paragraph

Review in Channels (Austin, Tex.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin Heinea RG Molecular Physiology, Leibniz Institute for Neurobiology, Center for Behavioral Brain Science, Otto-von-Guericke-University of Magdeburg , Magdeburg , Germany.
Anna Ciuraszkiewicza RG Molecular Physiology, Leibniz Institute for Neurobiology, Center for Behavioral Brain Science, Otto-von-Guericke-University of Magdeburg , Magdeburg , Germany.
Andreas Voigtb Lehrstuhl Systemverfahrenstechnik, Otto-von-Guericke-University of Magdeburg , Magdeburg , Germany.
Jennifer Hecka RG Molecular Physiology, Leibniz Institute for Neurobiology, Center for Behavioral Brain Science, Otto-von-Guericke-University of Magdeburg , Magdeburg , Germany.
Arthur Bikbaeva RG Molecular Physiology, Leibniz Institute for Neurobiology, Center for Behavioral Brain Science, Otto-von-Guericke-University of Magdeburg , Magdeburg , Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurons encode information in fast changes of the membrane potential, and thus electrical membrane properties are critically important for the integration and processing of synaptic inputs by a neuron. These electrical properties are largely determined by ion channels embedded in the membrane. The distribution of most ion channels in the membrane is not spatially uniform: they undergo activity-driven changes in the range of minutes to days. Even in the range of milliseconds, the composition and topology of ion channels are not static but engage in highly dynamic processes including stochastic or activity-dependent transient association of the pore-forming and auxiliary subunits, lateral diffusion, as well as clustering of different channels. In this review we briefly discuss the potential impact of mobile sodium, calcium and potassium ion channels and the functional significance of this for individual neurons and neuronal networks.

Indexed as

Calcium ChannelsMembrane PotentialsNeuronsPotassium Channels, Voltage-GatedSurface PropertiesVoltage-Gated Sodium ChannelsCalcium ChannelsPotassium Channels, Voltage-GatedVoltage-Gated Sodium Channelslateral diffusionmobilitysurface dynamicsvoltage gated ion channels

Identifiers

PMID26891382
PMCPMC4954569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.