Evidence map›Paper›PMID 26891321›Full record

ReviewNutrients2016

Myricetin: A Dietary Molecule with Diverse Biological Activities.

Deepak Kumar Semwal, Ruchi Badoni Semwal, Sandra Combrinck, Alvaro Viljoen

Abstract readReview
In one paragraph

Review in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 270 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
270citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

270 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. The effect of flavonoids on the doxorubicin efficacy in cancer treatment.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Review
  8. Review
  9. Article
  10. Metabolomic, in vitro and preclinical evaluation of Auricularia polytricha mushroom.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Bioactive Components ofAntioxidants (Basel, Switzerland) · 2026
    Review
  20. Review

210 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Deepak Kumar SemwalDepartment of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria 0001, South Africa. SemwalDK@tut.ac.za.
Ruchi Badoni SemwalDepartment of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria 0001, South Africa. SemwalRB@tut.ac.za.
Sandra CombrinckDepartment of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria 0001, South Africa. CombrinckS@tut.ac.za.
Alvaro ViljoenDepartment of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria 0001, South Africa. viljoenam@tut.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals value. It is one of the key ingredients of various foods and beverages. The compound exhibits a wide range of activities that include strong anti-oxidant, anticancer, antidiabetic and anti-inflammatory activities. It displays several activities that are related to the central nervous system and numerous studies have suggested that the compound may be beneficial to protect against diseases such as Parkinson's and Alzheimer's. The use of myricetin as a preserving agent to extend the shelf life of foods containing oils and fats is attributed to the compound's ability to protect lipids against oxidation. A detailed search of existing literature revealed that there is currently no comprehensive review available on this important molecule. Hence, the present work includes the history, synthesis, pharmaceutical applications and toxicity studies of myricetin. This report also highlights structure-activity relationships and mechanisms of action for various biological activities.

Indexed as

DietPhytotherapyAnimalsAnti-Infective AgentsAntineoplastic Agents, PhytogenicAntioxidantsFlavonoidsHumansNervous System DiseasesNeuroprotective AgentsPlant ExtractsPlants, EdibleAnti-Infective AgentsAntineoplastic Agents, PhytogenicAntioxidantsFlavonoidsmyricetinNeuroprotective AgentsPlant Extractsanti-alzheimer activityanti-HIV activityanti-oxidant activitycytotoxicitymyricetinpolyphenol

Identifiers

PMID26891321
PMCPMC4772053

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.