Evidence map›Paper›PMID 26891290›Full record

ArticleMolecules (Basel, Switzerland)2016

Bioactive ZnO Coatings Deposited by MAPLE-An Appropriate Strategy to Produce Efficient Anti-Biofilm Surfaces.

Alexandra Elena Oprea, Loredana Mihaela Pandel, Ana Maria Dumitrescu, Ecaterina Andronescu, Valentina Grumezescu, Mariana Carmen Chifiriuc, Laurenţiu Mogoantă, Tudor-Adrian Bălşeanu, George Dan Mogoşanu, Gabriel Socol and 5 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
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  6. Review
  7. Article
  8. Targeting microbial biofilms: byIET nanobiotechnology · 2020
    Article
  9. Vapor-Deposited Biointerfaces and Bacteria: An Evolving Conversation.ACS biomaterials science & engineering · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Alexandra Elena OpreaDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. elena_oprea_93@yahoo.co.uk.
Loredana Mihaela PandelDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. loredana.pandel@yahoo.com.
Ana Maria DumitrescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. ana_maria_dumitrescu@yahoo.com.
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. ec_andronescu@yahoo.com.
Valentina GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. valentina_grumezescu@yahoo.com.
Mariana Carmen ChifiriucMicrobiology Immunology Department, Faculty of Biology, University of Bucharest, 1-3 Portocalelor Lane, Sector 5, Bucharest 77206, Romania. carmen_balotescu@yahoo.com.
Laurenţiu MogoantăResearch Center for Microscopic Morphology and Immunology, University of Medicine and Pharmacy of Craiova, Petru Rares Street, No. 2, Craiova 200349, Romania. editor@rjme.ro.
Tudor-Adrian BălşeanuResearch Center for Clinical and Experimental Medicine, University of Medicine and Pharmacy of Craiova, Petru Rares Street, No. 2, Craiova 200349, Romania. adibalseanu@yahoo.com.
George Dan MogoşanuDepartment of Pharmacognosy & Phytotherapy, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Petru Rares Street, No. 2, Craiova 200349, Romania. mogosanu2006@yahoo.com.
Gabriel SocolLasers Department, National Institute for Lasers, Plasma & Materials, P. O. Box MG-36, Magurele 769231, Romania. gabriel.socol@inflpr.ro.
Alexandru Mihai GrumezescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. grumezescu@yahoo.com.
Florin IordacheFlow Cytometry and Cell Therapy Laboratory, Institute of Cellular Biology and Pathology "NicolaeSimionescu" (ICBP), Bucharest 050568, Romania. floriniordache84@yahoo.com.
Horia ManiuFlow Cytometry and Cell Therapy Laboratory, Institute of Cellular Biology and Pathology "NicolaeSimionescu" (ICBP), Bucharest 050568, Romania. horia.maniu@gmail.com.
Mariana ChireaDepartment of Electrical & Electronics Engineering, IDEALAB, Koç University, Rumeli Feneri Yolu, Sariyer, Istanbul 34450, Turkey. mchirea@ku.edu.tr.
Alina Maria HolbanDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest,1-7 Polizu Street, Bucharest 011061, Romania. alina_m_h@yahoo.com.
Universitatea Națională de Știință și Tehnologie Politehnica București · ROUniversity of Medicine and Pharmacy of Craiova · RONational Institute for Laser Plasma and Radiation Physics · RORomanian Academy · ROUniversity of Bucharest · ROKoç University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deposition of bioactive coatings composed of zinc oxide, cyclodextrin and cefepime (ZnO/CD/Cfp) was performed by the Matrix Assisted Pulsed Laser Evaporation (MAPLE) technique. The obtained nanostructures were characterized by X-ray diffraction, IR microscopy and scanning electron microscopy. The efficient release of cefepime was correlated with an increased anti-biofilm activity of ZnO/CD/Cfp composites. In vitro and in vivo tests have revealed a good biocompatibility of ZnO/CD/Cfp coatings, which recommend them as competitive candidates for the development of antimicrobial surfaces with biomedical applications. The release of the fourth generation cephalosporin Cfp in a biologically active form from the ZnO matrix could help preventing the bacterial adhesion and the subsequent colonization and biofilm development on various surfaces, and thus decreasing the risk of biofilm-related infections.

Indexed as

AnimalsAnti-Bacterial AgentsBiofilmsCefepimeCephalosporinsCoated Materials, BiocompatibleCyclodextrinsMiceNanostructuresX-Ray DiffractionZinc OxideAnti-Bacterial AgentsCefepimeCephalosporinsCoated Materials, BiocompatibleCyclodextrinsZinc Oxidebiofilm inhibitioncyclodextrinsdrug deliveryMAPLEmodified surfacezinc oxide

Identifiers

PMID26891290
PMCPMC6273712
OpenAlexW2278942625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.