ArticlePLoS neglected tropical diseases2016
Molecular Individual-Based Approach on Triatoma brasiliensis: Inferences on Triatomine Foci, Trypanosoma cruzi Natural Infection Prevalence, Parasite Diversity and Feeding Sources.
Article in PLoS neglected tropical diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Distribution, host origin, and transmission cycles of Trypanosoma cruzi genotypes in the State of Rio Grande do Norte, Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2025Pooled it
- Who Feeds theMicroorganisms · 2026Article
- The complexity of the population dynamics of Triatoma brasiliensis in rural north-east Brazil indicated by genetic characterisation.Memorias do Instituto Oswaldo Cruz · 2026Article
- First record of Triatoma vitticeps (Hemiptera, Reduviidae) colonising a brick house in an urban area of a devastated Atlantic Forest fragment in Rio de Janeiro State, Brazil.Memorias do Instituto Oswaldo Cruz · 2026Article
- A Brief History of the Use of Insecticides in Brazil to Control Vector-Borne Diseases, and Implications for Insecticide Resistance.Tropical medicine and infectious disease · 2025Review
- Genetic Identification of Brazilian Mammalian Hosts ofPathogens (Basel, Switzerland) · 2025Article
- The mitogenome of Triatoma brasiliensis brasiliensis (Hemiptera: Reduviidae), the main Chagas disease vector in the semi-arid region of northeastern Brazil.Parasites & vectors · 2025Article
- Home invasion of triatomines (Hemiptera: Reduviidae) in the urban area of Mato Grosso, Brazil.Revista da Sociedade Brasileira de Medicina Tropical · 2025Article
- Vector mapping and bloodmeal metabarcoding demonstrate risk of urban Chagas disease transmission in Caracas, Venezuela.PLoS neglected tropical diseases · 2023Article
- "Mi Casa, Tu Casa": the coati nest as a hub of Trypanosoma cruzi transmission in the southern Pantanal biome revealed by molecular blood meal source identification in triatomines.Parasites & vectors · 2023Article
- High Parasitic Loads Quantified in SylvaticPathogens (Basel, Switzerland) · 2022Article
- Genetic diversity in peridomiciliary populations of Triatoma mexicana (Hemiptera: Reduviidae: Triatominae) in central Mexico.Parasitology research · 2022Article
- Morphological Stasis in Time? AAnimals : an open access journal from MDPI · 2022Article
- Article
- Revisiting the Hybridization Processes in theInsects · 2021Article
- The connection between Trypanosoma cruzi transmission cycles by Triatoma brasiliensis brasiliensis: A threat to human health in an area susceptible to desertification in the Seridó, Rio Grande do Norte, Brazil.PLoS neglected tropical diseases · 2021Article
- Identification and characterization of microsatellite markers for population genetic studies of Panstrongylus megistus (Burmeister, 1835) (Triatominae: Reduviidae).Parasites & vectors · 2021Article
- Under pressure: phenotypic divergence and convergence associated with microhabitat adaptations in Triatominae.Parasites & vectors · 2021Article
- Triatomine Feeding Profiles andPathogens (Basel, Switzerland) · 2021Article
- Drivers of molecular and morphometric variation in Triatoma brasiliensis (Hemiptera: Triatominae): the resolution of geometric morphometrics for populational structuring on a microgeographical scale.Parasites & vectors · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used an individual-based molecular multisource approach to assess the epidemiological importance of Triatoma brasiliensis collected in distinct sites and ecotopes in Rio Grande do Norte State, Brazil. In the semi-arid zones of Brazil, this blood sucking bug is the most important vector of Trypanosoma cruzi--the parasite that causes Chagas disease. First, cytochrome b (cytb) and microsatellite markers were used for inferences on the genetic structure of five populations (108 bugs). Second, we determined the natural T. cruzi infection prevalence and parasite diversity in 126 bugs by amplifying a mini-exon gene from triatomine gut contents. Third, we identified the natural feeding sources of 60 T. brasiliensis by using the blood meal content via vertebrate cytb analysis. Demographic inferences based on cytb variation indicated expansion events in some sylvatic and domiciliary populations. Microsatellite results indicated gene flow between sylvatic and anthropic (domiciliary and peridomiciliary) populations, which threatens vector control efforts because sylvatic population are uncontrollable. A high natural T. cruzi infection prevalence (52-71%) and two parasite lineages were found for the sylvatic foci, in which 68% of bugs had fed on Kerodon rupestris (Rodentia: Caviidae), highlighting it as a potential reservoir. For peridomiciliary bugs, Galea spixii (Rodentia: Caviidae) was the main mammal feeding source, which may reinforce previous concerns about the potential of this animal to link the sylvatic and domiciliary T. cruzi cycles.
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