Evidence map›Paper›PMID 26890830›Full record

ReviewMagnetic resonance in medicine2016

Safety and technique of ferumoxytol administration for MRI.

Shreyas S Vasanawala, Kim-Lien Nguyen, Michael D Hope, Mellena D Bridges, Thomas A Hope, Scott B Reeder, Mustafa R Bashir

Registry-linked trialAbstract readReview
In one paragraph

Review in Magnetic resonance in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06483061 (Ferumoxytol Enhanced Hippocampal Vascular Imaging in Epilepsy), which is not on this map. Cited by 108 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06483061 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Ferumoxytol Enhanced Hippocampal Vascular Imaging in Epilepsy

TypeinterventionalSponsorUniversity of AlbertaRan2025 to 2029Enrolled50ConditionsEpilepsy, Temporal LobeArmsFerumoxytol
3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
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  11. Article
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  14. Pharmacokinetic Study of Ultrasmall Superparamagnetic Iron Oxide Nanoparticles HY-088 in Rats.European journal of drug metabolism and pharmacokinetics · 2024
    Article
  15. Article
  16. Article
  17. IV iron formulations and use in adults.Hematology. American Society of Hematology. Education Program · 2023
    Article
  18. Article
  19. Article
  20. 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shreyas S VasanawalaDepartment of Radiology, Stanford University, Stanford, CA.
Kim-Lien NguyenDepartment of Medicine, David Geffen School of Medicine at UCLA, University of California, Los Angeles.
Michael D HopeDepartment of Radiology, University of California, San Francisco.
Mellena D BridgesDepartment of Radiology, Mayo Clinic Florida, Jacksonville, FL.
Thomas A HopeDepartment of Radiology, University of California, San Francisco.
Scott B ReederDepartments of Radiology, Medical Physics, Biomedical Engineering, and Emergency Medicine, University of Wisconsin, Madison, WI.
Mustafa R BashirCenter for Advanced Magnetic Resonance Development and Department of Radiology, Duke University, Durham, NC.

Funding

Confounder-Corrected Quantitative MRI Biomarkers of HepaticR01DK100651 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2017
$2.7M
Hemodynamic and inflammatory imaging in evaluation of abdominal aortic aneurysmsR01HL123759 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HOPE, MICHAEL DOUGLAS · 2015 to 2018
$1.6M
NHLBI NIH HHS R01 HL123759NIDDK NIH HHS R01 DK100651
6 · The paper itself

Abstract

Ferumoxytol is an ultrasmall superparamagnetic iron oxide agent marketed for the treatment of anemia. There has been increasing interest in its properties as an MRI contrast agent as well as greater awareness of its adverse event profile. This mini-review summarizes the current state of knowledge of the risks of ferumoxytol and methods of administration.

Indexed as

Magnetic Resonance ImagingClinical Trials as TopicContrast MediaFerric CompoundsFerrosoferric OxideGadoliniumHumansIodineMacrophagesNeoplasm MetastasisNeoplasmsPatient SafetyPerfusionContrast MediaFerric Compoundsferric oxideFerrosoferric OxideGadoliniumIodinecontrast agentferumoxytoliron oxidesafety

Identifiers

PMID26890830
PMCPMC4854636

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.