ArticlePloS one2016
Time-Course Transcriptome Analysis Reveals Resistance Genes of Panax ginseng Induced by Cylindrocarpon destructans Infection Using RNA-Seq.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
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- Interaction of Ginseng withPlants (Basel, Switzerland) · 2022Review
- Comparative transcriptome analysis of resistant and susceptible wheat in response to Rhizoctonia cerealis.BMC plant biology · 2022Article
- Genome-wide identification and transcriptional profiling analysis ofChinese herbal medicines · 2022Article
- Regulatory network of ginsenoside biosynthesis under Ro stress in the hairy roots ofFrontiers in bioengineering and biotechnology · 2022Article
- Molecular Identification and Analysis on Differential Pathogenicity ofFrontiers in plant science · 2022Article
- Exploring sunflower responses to Sclerotinia head rot at early stages of infection using RNA-seq analysis.Scientific reports · 2020Article
- Till 2018: a survey of biomolecular sequences in genusJournal of ginseng research · 2020Review
- Silicon confers protective effect against ginseng root rot by regulating sugar efflux into apoplast.Scientific reports · 2019Article
- Using a transcriptome sequencing approach to explore candidate resistance genes against stemphylium blight in the wild lentil species Lens ervoides.BMC plant biology · 2019Article
- Comparative transcriptome analyses on terpenoids metabolism in field- and mountain-cultivated ginseng roots.BMC plant biology · 2019Article
- Soil fungal biodiversity and pathogen identification of rotten disease in Aconitum carmichaelii (Fuzi) roots.PloS one · 2018Article
- Comprehensive Characterization for Ginsenosides Biosynthesis in Ginseng Root by Integration Analysis of Chemical and Transcriptome.Molecules (Basel, Switzerland) · 2017Article
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9 authors.
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Abstract
Panax ginseng C. A. Meyer is a highly valued medicinal plant. Cylindrocarpon destructans is a destructive pathogen that causes root rot and significantly reduces the quality and yield of P. ginseng. However, an efficient method to control root rot remains unavailable because of insufficient understanding of the molecular mechanism underlying C. destructans-P. ginseng interaction. In this study, C. destructans-induced transcriptomes at different time points were investigated using RNA sequencing (RNA-Seq). De novo assembly produced 73,335 unigenes for the P. ginseng transcriptome after C. destructans infection, in which 3,839 unigenes were up-regulated. Notably, the abundance of the up-regulated unigenes sharply increased at 0.5 d postinoculation to provide effector-triggered immunity. In total, 24 of 26 randomly selected unigenes can be validated using quantitative reverse transcription (qRT)-PCR. Gene ontology enrichment analysis of these unigenes showed that "defense response to fungus", "defense response" and "response to stress" were enriched. In addition, differentially expressed transcription factors involved in the hormone signaling pathways after C. destructans infection were identified. Finally, differentially expressed unigenes involved in reactive oxygen species and ginsenoside biosynthetic pathway during C. destructans infection were indentified. To our knowledge, this study is the first to report on the dynamic transcriptome triggered by C. destructans. These results improve our understanding of disease resistance in P. ginseng and provide a useful resource for quick detection of induced markers in P. ginseng before the comprehensive outbreak of this disease caused by C. destructans.
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