ArticleEmerging infectious diseases2016
Faster Detection of Poliomyelitis Outbreaks to Support Polio Eradication.
Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Cluster Detection Mechanisms for Syndromic Surveillance Systems: Systematic Review and Framework Development.JMIR public health and surveillance · 2020Pooled it
- Assessing early detection ability through spatial arrangements in environmental surveillance for poliovirus: A simulation-based study.PloS one · 2025Article
- The Origins and Risk Factors for Serotype-2 Vaccine-Derived Poliovirus Emergences in Africa During 2016-2019.The Journal of infectious diseases · 2023Article
- Real-time prediction model of cVDPV2 outbreaks to aid outbreak response vaccination strategies.Vaccine · 2023Article
- Article
- Enterovirus Surveillance (EVSurv) in Germany.Microorganisms · 2021Article
- Review of poliovirus modeling performed from 2000 to 2019 to support global polio eradication.Expert review of vaccines · 2020Review
- Evaluating the reliability and validity of secondary reporting to measure gender-based violence in conflict and disaster.Conflict and health · 2020Article
- Precision Surveillance for Viral Respiratory Pathogens: Virome Capture Sequencing for the Detection and Genomic Characterization of Severe Acute Respiratory Infection in Uganda.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019Article
- Profile of polio-compatible cases in Nigeria, 2006-2016.BMC public health · 2018Article
- Type 2 Poliovirus Detection after Global Withdrawal of Trivalent Oral Vaccine.The New England journal of medicine · 2018Article
- Polio outbreaks in the post-COVID-19 pandemic era: causes and solutions.Pathogens and global healthReview
- Finding Outbreaks Faster.Health securityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
As the global eradication of poliomyelitis approaches the final stages, prompt detection of new outbreaks is critical to enable a fast and effective outbreak response. Surveillance relies on reporting of acute flaccid paralysis (AFP) cases and laboratory confirmation through isolation of poliovirus from stool. However, delayed sample collection and testing can delay outbreak detection. We investigated whether weekly testing for clusters of AFP by location and time, using the Kulldorff scan statistic, could provide an early warning for outbreaks in 20 countries. A mixed-effects regression model was used to predict background rates of nonpolio AFP at the district level. In Tajikistan and Congo, testing for AFP clusters would have resulted in an outbreak warning 39 and 11 days, respectively, before official confirmation of large outbreaks. This method has relatively high specificity and could be integrated into the current polio information system to support rapid outbreak response activities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.