ArticleHuman vaccines & immunotherapeutics2016
The role of B. pertussis vaccine antigen gene variants in pertussis resurgence and possible consequences for vaccine development.
Article in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- BPZE1 vaccination induces IL-17NPJ vaccines · 2026Article
- Breakthrough infections and incomplete vaccine efficacy drive pathogen immune escape.PloS one · 2026Article
- Evolution of tetraspanin antigens in the zoonotic Asian blood fluke Schistosoma japonicum.Parasites & vectors · 2023Article
- Characterization ofPathogens (Basel, Switzerland) · 2022Article
- Fha DeficientIranian journal of public health · 2021Article
- Pertussis in early life: underdiagnosed, severe, and risky disease. A seven-year experience in a pediatric tertiary-care hospital.Human vaccines & immunotherapeutics · 2021Article
- Comparative genomics of whole-cell pertussis vaccine strains from India.BMC genomics · 2020Article
- Article
- The evolution of Bordetella pertussis has selected for mutations of acr that lead to sensitivity to hydrophobic molecules and fatty acids.Emerging microbes & infections · 2019Article
- A curated genome-scale metabolic model of Bordetella pertussis metabolism.PLoS computational biology · 2017Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whooping cough, or pertussis, caused by Bordetella pertussis is considered resurgent in a number of countries world-wide, despite continued high level vaccine coverage. Among a number of causes for this that have been proposed, is the emergence of B. pertussis strains expressing variants of the antigens contained in acellular pertussis vaccines; i.e. the evolution of B. pertussis toward vaccine escape. This commentary highlights the contradictory nature of evidence for this but also discusses the importance of understanding the role of B. pertussis adaptation to vaccine-mediated immune selection pressures for vaccine-mediated pertussis control strategies.
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Registered trials
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