Evidence map›Paper›PMID 26889496›Full record

ArticleMovement disorders clinical practice2015

Ocular palatal tremor plus dystonia - new syndromic association.

Aasef G Shaikh, Fatema F Ghasia, Mahlon R DeLong, H A Jinnah, Alan Freeman, Stewart A Factor

Open access · greenAbstract read
In one paragraph

Article in Movement disorders clinical practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Lessons learned from the syndrome of oculopalatal tremor.Journal of computational neuroscience · 2021
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aasef G Shaikh
Fatema F Ghasia
Mahlon R DeLong
H A Jinnah
Alan Freeman
Stewart A Factor
Emory University · USCleveland Clinic · US

Funding

Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
OCULAR MOTOR DISORDERSR01EY006717 · NEI · CASE WESTERN RESERVE UNIVERSITY · PI LEIGH, RICHARD JOHN · 1987 to 2012
$1.8M
NCATS NIH HHS U54 TR001456NEI NIH HHS R01 EY006717NINDS NIH HHS U54 NS065701
6 · The paper itself

Abstract

objectiveOcular palatal tremor typically develops after a breach in the Guillian-Mollaret triangle. We herein describe a variant of this syndrome in which dystonia is also present, hence called, here, ocular palatal tremor plus dystonia.

methodsWe assessed eye-head movements and dystonia in six patients with ocular palatal plus dystonia.

resultsAmong six patients with ocular palatal tremor two had focal dystonia, three had multifocal dystonia, and one had generalized dystonia. The dystonia affected the upper extremities and neck in four patients, the lower extremities in three and the face in two. Three out of four cervical dystonia patients had head tremor. Two patients also had speech involvement. Lack of correlation between eye and head oscillations suggested that head oscillations were not compensatory or secondary to the eye oscillations and vice versa.

conclusionsWe describe a novel variant of ocular palatal tremor with dystonia. We speculate that in such variant the dystonia is possibly could be a result of abnormal cerebellar outflow in patients with a breach in Guillain-Mollaret triangle.

Indexed as

brainstemcerebelluminferior olivenystagmusoscillation

Identifiers

PMID26889496
PMCPMC4753074
OpenAlexW1498503517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.