Evidence map›Paper›PMID 26889474›Full record

ArticleCase reports in nephrology and dialysis

Successful Treatment of Dual-Positive Anti-Myeloperoxidase and Anti-Glomerular Basement Membrane Antibody Vasculitis with Pulmonary-Renal Syndrome.

Jinxian Huang, Ling Wu, Xiaoyan Huang, Yan Xie, Jinquan Yu, Jin Yang, Huiqiong Fang, Lijun Zhang

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in nephrology and dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Jinxian HuangRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Ling WuRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Xiaoyan HuangRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Yan XieRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Jinquan YuRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Jin YangRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Huiqiong FangRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Lijun ZhangRheumatology Department, The University of Hong Kong Shenzhen Hospital, Shenzhen, China.
University of Hong Kong · HKUniversity of Hong Kong - Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and anti-glomerular basement membrane (GBM) disease are two separate diseases, while sometimes they can coexist together. The exact mechanisms are not clear, but due to the rapid progression and poor prognosis, prompt and aggressive treatment is usually required. We treated with steroids combined with cyclophosphamide and rituximab an 84-year-old man with ANCA-associated vasculitis and anti-GBM disease who had prior pulmonary fibrosis and a coexisting anterosuperior mediastinal mass. Conventional therapy including steroids, plasmapheresis and cyclophosphamide failed to attenuate the anti-GBM disease, yet he responded to an alternative treatment of rituximab. This case suggests the efficacy of steroids and immunosuppressant for the treatment of a dual-positive case with an anterosuperior mediastinal mass.

Indexed as

Anti-glomerular basement membrane antibodyMediastinal massMyeloperoxidase-antineutrophil cytoplasmic antibodyPulmonary fibrosisVasculitis

Identifiers

PMID26889474
PMCPMC4748756
OpenAlexW2223669111

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.