ArticleAsian journal of neurosurgery
The impact of cranioplasty on cerebral blood flow and its correlation with clinical outcome in patients underwent decompressive craniectomy.
Article in Asian journal of neurosurgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Timing for cranioplasty to improve neurological outcome: A systematic review.Brain and behavior · 2018Pooled it
- The Effect of Cranioplasty on Cerebrospinal Fluid Dynamics in the Cerebral Aqueduct.Journal of Korean Neurosurgical Society · 2026Article
- Timing and Outcomes of Cranioplasty After Decompressive Craniectomy: A Systematic Review of Neurological Recovery, Complications, and Predictive Factors.Journal of clinical medicine · 2026Review
- The current state of cranioplasty in Europe - Results from a European cranioplasty survey.Brain & spine · 2025Article
- Article
- Three-dimensional personalized porous polyethylen cranioplasty in patients at increased risk of surgical site infection.Acta neurochirurgica · 2024Article
- Complication rates after autologous cranioplasty following decompressive craniectomy.Acta neurochirurgica · 2024Article
- Cranioplasty in Oman: Retrospective review of cases from the National Craniofacial Center 2012-2022.Sultan Qaboos University medical journal · 2024Article
- Malignant cerebral edema after cranioplasty, a rare complication: case series and literature review.Annals of medicine and surgery (2012) · 2023Article
- Clinical improvement after cranioplasty and its relation to body position and cerebral hemodynamics.Neurosurgical review · 2022Article
- Parkinsonism-like features following reconstructive cranioplasty.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Osteoblast and Bacterial Culture from Cryopreserved Skull Flap after Craniectomy: Laboratory Study.Journal of Korean Neurosurgical Society · 2017Article
- Fatal cerebral swelling immediately after cranioplasty: A case report.Surgical neurology international · 2017Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextDecompressive craniectomy is commonly use as the treatment for medically refractory intracranial hypertension. Unexpected improvement in patient's neurological status has been observed among patients that underwent cranioplasty. Restoration of cerebral blood flow (CBF) hemodynamics is one of the contributing factors. This study was conducted to determine the impact of cranioplasty on CBF and its correlation with clinical outcome.
aimsThis study was done to evaluate the effect of cranioplasty on CBF with computed tomography perfusion (CTP). It also aimed to determine the correlation between postcranioplasty CBF and clinical outcome. SETTINGS AND
designProspective observational study. SUBJECTS AND
methodsAll patients had CTP done to determine precranioplasty CBF. CTP was repeated at 6 weeks postcranioplasty and clinical assessment at 6 and 24 weeks postcranioplasty. STATISTICAL ANALYSIS USED: Data analysis was done using Statistical Package for Social Sciences version 12.0.1.
resultsThe median value of the ipsilateral CBF was 48.87 and 61.10 ml/min/100 g at precranioplasty and 6 weeks postcranioplasty (P < 0.001). Contralateral CBF also showed improvement from 60.55 to 71.84 ml/min/100 g (P < 0.001). Median value for mini mental state examination showed a significant difference with value of 22, 25, and 25.5 at precranioplasty, 6 and 24 weeks postcranioplasty (P = 0.001 and P < 0.001). Median value for frontal assessment battery was 12, 14.5, and 15 (P = 0.002 and P = 0.001).
conclusionsCranioplasty can remarkably improve cortical perfusion for both ipsilateral and contralateral hemisphere. Though we are unable to establish strong correlation, between CBF and clinical outcome, cranioplasty was observed to have a therapeutic role in terms of clinical outcome improvement.
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