Evidence map›Paper›PMID 26889254›Full record

ArticleExperimental and therapeutic medicine2016

Protocatechuic aldehyde inhibits TNF-α-induced fibronectin expression in human umbilical vein endothelial cells via a c-Jun N-terminal kinase dependent pathway.

Yue-Feng Tong, Yong Liu, Zhi-Xing Hu, Zhe-Cheng Li, Agula A

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  10. Alpha-mangostin decreased cellular senescence in human umbilical vein endothelial cells.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yue-Feng TongDivision of Cardiology, The First Yongkang Municipal Hospital, Yongkang, Zhejiang 321300, P.R. China.
Yong LiuBeijing Institute of Radiation Medicine, Beijing 100850, P.R. China.
Zhi-Xing HuDivision of Cardiology, The First Yongkang Municipal Hospital, Yongkang, Zhejiang 321300, P.R. China.
Zhe-Cheng LiDivision of Cardiology, The First Yongkang Municipal Hospital, Yongkang, Zhejiang 321300, P.R. China.
Agula ABeijing Institute of Radiation Medicine, Beijing 100850, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibronectin (FN) is one of the most important extracellular matrix proteins and plays an important role in the pathogenesis of atherosclerosis (AS). The aim of the present study was to evaluate the effect of a potent, water-soluble antioxidant, protocatechuic aldehyde (PA), which is derived from the Chinese herb

Indexed as

endothelial cellfibronectinmitogen-activated protein kinaseprotocatechuic aldehydetumor necrosis factor-α

Identifiers

PMID26889254
PMCPMC4727035
OpenAlexW2178133831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.