Evidence map›Paper›PMID 26889016›Full record

ReviewPhysiology (Bethesda, Md.)2016

Obesity, Asthma, and the Microbiome.

Youngji Cho, Stephanie A Shore

Open access · bronzeAbstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. What Makes the Gut-Lung Axis Working? From the Perspective of Microbiota and Traditional Chinese Medicine.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
  2. Review
  3. Review
  4. Review
  5. Obesity-related asthma in children and adolescents.The Lancet. Child & adolescent health · 2022
    Review
  6. Review
  7. Review
  8. Review
  9. Childhood Obesity and Respiratory Diseases: Which Link?Children (Basel, Switzerland) · 2021
    Review
  10. Obesity and severe asthma.Allergology international : official journal of the Japanese Society of Allergology · 2019
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Obesity and Asthma: Microbiome-Metabolome Interactions.American journal of respiratory cell and molecular biology · 2016
    Review
  17. Review
  18. Staphylococcal superantigen-specific IgE antibodies: degree of sensitization and association with severity of asthma.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Youngji ChoDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Stephanie A ShoreDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts sshore@hsph.harvard.edu.
Harvard University · US

Funding

Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SUSAN A KORRICK · 1985 to 2026
$44.6M
Impact of Obesity on Airway Responses to Air PollutionR01ES013307 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI SHORE, STEPHANIE A · 2005 to 2019
$5.2M
Obesity and asthma: microbiome-metabolome interactionsR21ES024032 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI SHORE, STEPHANIE A · 2015 to 2016
$444k
NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES013307NIEHS NIH HHS R21 ES024032
6 · The paper itself

Abstract

Obesity is a risk factor for asthma, but standard asthma drugs have reduced efficacy in the obese. Obesity alters the gastrointestinal microbial community structure. This change in structure contributes to some obesity-related conditions and also could be contributing to obesity-related asthma. Although currently unexplored, obesity may also be altering lung microbiota. Understanding the role of microbiota in obesity-related asthma could lead to novel treatments for these patients.

Indexed as

AnimalsAsthmaGastrointestinal TractHumansLungMicrobiotaObesityRisk Factors

Identifiers

PMID26889016
PMCPMC4888975
OpenAlexW2283296055

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.