ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2016
Cell-Type Specific Phase Precession in Layer II of the Medial Entorhinal Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- Ultra-high-density Neuropixels probes improve detection and identification in neuronal recordings.Neuron · 2025Article
- Theta-phase locking of single neurons during human spatial memory.Nature communications · 2025Article
- Ultra-high density electrodes improve detection, yield, and cell type identification in neuronal recordings.bioRxiv : the preprint server for biology · 2024Article
- Phase information is conserved in sparse, synchronous population-rate-codes via phase-to-rate recoding.Nature communications · 2023Article
- Article
- Quantitative optical coherence microscopy of neuron morphology in human entorhinal cortex.Frontiers in neuroscience · 2023Article
- Cell type, sub-region, and layer-specific speed representation in the hippocampal-entorhinal circuit.Scientific reports · 2020Article
- The neural circuitry supporting successful spatial navigation despite variable movement speeds.Neuroscience and biobehavioral reviews · 2020Review
- Replay as wavefronts and theta sequences as bump oscillations in a grid cell attractor network.eLife · 2019Article
- Hippocampal Sequences During Exploration: Mechanisms and Functions.Frontiers in cellular neuroscience · 2019Review
- Recurrent circuits within medial entorhinal cortex superficial layers support grid cell firing.Nature communications · 2018Article
- Glutamatergic synaptic integration of locomotion speed via septoentorhinal projections.Nature neuroscience · 2017Article
- Cell Type-Specific Differences in Spike Timing and Spike Shape in the Rat Parasubiculum and Superficial Medial Entorhinal Cortex.Cell reports · 2016Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identity of phase-precessing cells in the entorhinal cortex is unknown. Here, we used a classifier derived from cell-attached recordings to separate putative pyramidal cells and putative stellate cells recorded extracellularly in layer II of the medial entorhinal cortex in rats. Using a novel method to identify single runs as temporal periods of elevated spiking activity, we find that both cell types show phase precession but putative stellate cells show steeper slopes of phase precession and larger phase ranges. As the two classes of cells have different projection patterns, phase precession is differentially passed on to different subregions of the hippocampal formation. SIGNIFICANCE STATEMENT: It is a great challenge for neuroscience to reveal the cellular basis of cognitive functions. One such function is the ability to learn and recollect temporal sequences of events. The representation of sequences in the brain is thought to require temporally structured activity of nerve cells. How different types of neurons generate temporally structured activity is currently unknown. In the present study, we use a computational classification procedure to separate different cell types and find that a subpopulation of cells, so-called stellate neurons, exhibits clear temporal coding. Contrary to the stellate cells, pyramidal cells show weaker temporal coding. This discovery sheds light on the cellular basis of temporal coding in the brain.
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