ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016
Low temperature plasmas as emerging cancer therapeutics: the state of play and thoughts for the future.
Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed, 151 citations in OpenAlex.
- Effect of Low-Temperature Plasma on Porcine Oocytes In Vitro Primary Culture.Antioxidants (Basel, Switzerland) · 2026Article
- The effects of ex vivo physical cold atmospheric plasma treatment on endothelial cells in human corneal explants and its potential for in vivo application in refractory corneal ulcers.Scientific reports · 2025Article
- Risk factors behind the global lung cancer burden: a pan-database exploration.Translational lung cancer research · 2025Article
- Cold atmospheric plasma effectively kills chordoma cells through induction of intracellular reactive oxygen species.Scientific reports · 2025Article
- Apoptotic effects of cold atmospheric pressure plasma on A549 and LL/2 lung carcinoma cell lines.Scientific reports · 2025Article
- Low-temperature plasma improves the healing process of Achilles tendinopathy in a rat model.Frontiers in bioengineering and biotechnology · 2025Article
- Cold Plasma Activity Against Biofilm Formation of Prosthetic Joint Infection Pathogens.Pathogens (Basel, Switzerland) · 2024Article
- Effect of plasma-induced oxidation on NK cell immune checkpoint ligands: A computational-experimental approach.Redox biology · 2024Article
- Fracture healing on non-union fracture model promoted by non-thermal atmospheric-pressure plasma.PloS one · 2024Article
- Low temperature plasma protects against inflammatory agents-mediated dysfunction of theca cells via enhancing MANF expression.Molecular biology reports · 2023Article
- Low temperature plasma suppresses proliferation, invasion, migration and survival of SK-BR-3 breast cancer cells.Molecular biology reports · 2023Article
- Argon cold atmospheric plasma eradicates pathogensFrontiers in veterinary science · 2023Article
- Differential Sensitivity of Melanoma Cells and Their Non-Cancerous Counterpart to Cold Atmospheric Plasma-Induced Reactive Oxygen and Nitrogen Species.International journal of molecular sciences · 2022Article
- Cold Atmospheric Plasma Suppressed MM In Vivo Engraftment by Increasing ROS and Inhibiting the Notch Signaling Pathway.Molecules (Basel, Switzerland) · 2022Article
- Preclinical Cold Atmospheric Plasma Cancer Treatment.Cancers · 2022Review
- Cold Argon Athmospheric Plasma for Biomedicine: Biological Effects, Applications and Possibilities.Antioxidants (Basel, Switzerland) · 2022Review
- Insight into the Impact of Oxidative Stress on the Barrier Properties of Lipid Bilayer Models.International journal of molecular sciences · 2022Article
- Cold Atmospheric Plasma Reduces Vessel Density and Increases Vascular Permeability and Apoptotic Cell Death in Solid Tumors.Cancers · 2022Article
- Nanosecond-pulsed DBD plasma treatment on human leukaemia Jurkat cells and monoblastic U937 cells in vitro.Scientific reports · 2022Article
- In Vivo Metabolic Analysis of the Anticancer Effects of Plasma-Activated Saline in Three Tumor Animal Models.Biomedicines · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The field of plasma medicine has seen substantial advances over the last decade, with applications developed for bacterial sterilisation, wound healing and cancer treatment. Low temperature plasmas (LTPs) are particularly suited for medical purposes since they are operated in the laboratory at atmospheric pressure and room temperature, providing a rich source of reactive oxygen and nitrogen species (RONS). A great deal of research has been conducted into the role of reactive species in both the growth and treatment of cancer, where long-established radio- and chemo-therapies exploit their ability to induce potent cytopathic effects. In addition to producing a plethora of RONS, LTPs can also create strong electroporative fields. From an application perspective, it has been shown that LTPs can be applied precisely to a small target area. On this basis, LTPs have been proposed as a promising future strategy to accurately and effectively control and eradicate tumours. This review aims to evaluate the current state of the literature in the field of plasma oncology and highlight the potential for the use of LTPs in combination therapy. We also present novel data on the effect of LTPs on cancer stem cells, and speculatively outline how LTPs could circumvent treatment resistance encountered with existing therapeutics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.