Evidence map›Paper›PMID 26886963›Full record

ArticleIEEE transactions on bio-medical engineering2016

Scattering and Diffraction of Elastodynamic Waves in a Concentric Cylindrical Phantom for MR Elastography.

Benjamin L Schwartz, Ziying Yin, Temel K Yasar, Yifei Liu, Altaf A Khan, Allen Q Ye, Thomas J Royston, Richard L Magin

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Benjamin L Schwartz
Ziying Yin
Temel K Yasar
Yifei Liu
Altaf A Khan
Allen Q Ye
Thomas J Royston
Richard L Magin

Funding

MR Monitoring of Engineered TissuesR01EB007537 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MAGIN, RICHARD L · 2009 to 2012
$1.7M
The Audible Human ProjectR01EB012142 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ROYSTON, THOMAS J · 2010 to 2013
$1.3M
NIBIB NIH HHS R01 EB007537NIBIB NIH HHS R01 EB012142
6 · The paper itself

Abstract

aimThe focus of this paper is to report on the design and construction of a multiply connected phantom for use in magnetic resonance elastography (MRE)-an imaging technique that allows for the noninvasive visualization of the displacement field throughout an object from externally driven harmonic motion-as well as its inverse modeling with a closed-form analytic solution which is derived herein from first principles.

methodsMathematically, the phantom is described as two infinite concentric circular cylinders with unequal complex shear moduli, harmonically vibrated at the exterior surface in a direction along their common axis. Each concentric cylinder is made of a hydrocolloid with its own specific solute concentration. They are assembled in a multistep process for which custom scaffolding was designed and built. A customized spin-echo-based MR elastography sequence with a sinusoidal motion-sensitizing gradient was used for data acquisition on a 9.4 T Agilent small-animal MR scanner. Complex moduli obtained from the inverse model are used to solve the forward problem with a finite-element method.

resultsBoth complex shear moduli show a significant frequency dependence (p 0.001) in keeping with previous work.

conclusionThe novel multiply connected phantom and mathematical model are validated as a viable tool for MRE studies. SIGNIFICANCE: On a small enough scale much of physiology can be mathematically modeled with basic geometric shapes, e.g., a cylinder representing a blood vessel. This study demonstrates the possibility of elegant mathematical analysis of phantoms specifically designed and carefully constructed for biomedical MRE studies.

Indexed as

Phantoms, ImagingAlgorithmsElasticity Imaging TechniquesMagnetic Resonance ImagingModels, BiologicalScattering, Radiation

Identifiers

PMID26886963
PMCPMC5097039

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.