Evidence map›Paper›PMID 26886873›Full record

ArticleDermatology and therapy2016

New Patient-Oriented Tools for Assessing Atrophic Acne Scarring.

Alison Layton, Brigitte Dréno, Andrew Y Finlay, Diane Thiboutot, Sewon Kang, Vicente Torres Lozada, Valerie Bourdès, Vincenzo Bettoli, Laurent Petit, Jerry Tan

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 6 countries.

Alison LaytonDepartment of Dermatology, Harrogate District Hospital, Harrogate, UK.
Brigitte DrénoDepartment of Dermatology, Hotel Dieu, Nantes, France.
Andrew Y FinlayDepartment of Dermatology, Cardiff University School of Medicine, Cardiff, UK.
Diane ThiboutotDepartment of Dermatology, Hershey University, Hershey, PA, USA.
Sewon KangDepartment of Dermatology, Johns Hopkins School of Medicine, Baltimore, MA, USA.
Vicente Torres LozadaDepartment of Dermatology, Juarez Hospital, Mexico City, Mexico.
Valerie BourdèsGalderma R & D, Sophia Antipolis, France. valerie.bourdes@galderma.com.
Vincenzo BettoliDepartment of Dermatology, University of Ferrara, Ferrara, Italy.
Laurent PetitGalderma R & D, Sophia Antipolis, France.
Jerry TanDepartment of Dermatology, University of Western Ontario, Windsor, Canada.
Galderma (France) · FRCardiff University · GBHarrogate District Hospital · GBHershey (United States) · USHospital Juárez de México · MXHôtel-Dieu de Paris · FRJohns Hopkins Medicine · USUniversity of Ferrara · ITWestern University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionScarring on visible areas such as the face is associated with negative psychological impact. Many patients with acne have clinically relevant scarring for which they seek treatment, implying that there is an impact on their lives. Currently there are no validated tools to assess the burden of atrophic acne scarring from the patient's perspective or to assess treatment benefit.

methodsTwo patient-reported outcome measures, the self-assessment of clinical acne-related scars (SCARS) and the facial acne scar quality of life (FASQoL) tools, both specific to facial atrophic acne scarring, were developed according to Food and Drug Administration guidance methodology. Patient interviews were conducted first to elicit patient-important concepts about scarring, then to validate patients' understanding of wording in the tools. These tools focus on symptoms (SCARS) and psychological and social well-being (FASQoL) and were designed to be suitable for self-completion and to be rapidly completed (2-5 min) within a clinical research setting.

resultsConcept elicitation interviews were conducted with 30 subjects and cognitive interviews with 20 subjects. With acne scarring, important concepts for patients included size, surface area affected, counts, and depth. The SCARS and FASQoL tools were shown to address relevant concepts that were easily understood by patients.

conclusionTwo patient-reported measures, SCARS and FASQoL, have been developed to help clinicians assess the severity and impact of acne scars. Responsivity of these instruments to treatment will require further evaluation.

fundingGalderma R&D, Sophia Antipolis, France.

Indexed as

AcneAtrophic scarPatient-reported outcome measureQuality of lifeScar assessment

Identifiers

PMID26886873
PMCPMC4906116
OpenAlexW2288009363

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.