Evidence map›Paper›PMID 26886750›Full record

ArticleCellular and molecular neurobiology2016

Shengmai Formula Ameliorates Pathological Characteristics in AD C. elegans.

Weimin Zhang, Dejuan Zhi, Hui Ren, Dong Wang, Xin Wang, Zhanxin Zhang, Dongqing Fei, Hongmei Zhu, Hongyu Li

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Journal of traditional and complementary medicine · 2023
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Weimin ZhangGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Dejuan ZhiGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Hui RenGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Dong WangInstitute of Microbiology, School of Life Sciences, Lanzhou University, Lanzhou, China.
Xin WangGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Zhanxin ZhangGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Dongqing FeiGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Hongmei ZhuGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China.
Hongyu LiGansu High Throughput Screening and Creation Center for Health Products, School of Pharmacy, Lanzhou University, No. 199, Donggang West Road, Lanzhou, 730000, China. lihy@lzu.edu.cn.
Lanzhou University · CN

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Shengmai (SM) formula, a classical traditional Chinese medicine formula, is composed of Panax ginseng (Pg), Ophiopogon japonicus (Oj), and Schisandra Chinesis (Sc). SM has been clinically used to treat heart failure and ischemic heart disease. Although SM formula has been reported to be potential for fighting against Alzheimer's disease (AD) by previous works, there are many gaps in our knowledge on its usage in AD treatment on an organism level and will then need to be further clarified. In this study, transgenic Caenorhabditis elegans expressing human Aβ

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansChemotaxisDisease Models, AnimalDrug CombinationsDrugs, Chinese HerbalHumansOphiopogonPanaxParalysisPeptide FragmentsSchisandraAmyloid beta-Peptidesamyloid beta-protein (1-42)Drug CombinationsDrugs, Chinese Herbalfructus schizandrae, radix ginseng, radix ophiopogonis drug combinationPeptide FragmentsADCaenorhabditis elegansChemotaxisParalysisSM formulaSynergistic effect

Identifiers

PMID26886750
PMCPMC11482344
OpenAlexW2473862115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.