ArticleJournal of biomedical optics2016
Biologically relevant photoacoustic imaging phantoms with tunable optical and acoustic properties.
Article in Journal of biomedical optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
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Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Image Quality Improvement Techniques and Assessment Adequacy in Clinical Optoacoustic Imaging: A Systematic Review.Biosensors · 2022Pooled it
- Open-source, low-cost 3D-printable testbed for in-body optical wireless communications research.HardwareX · 2026Article
- Blood-mimicking dye phantoms for evaluating photoacoustic oximetry accuracy.Photoacoustics · 2026Article
- Design and characterisation of intervertebral disc mimicking phantoms for photoacoustic imaging.Photoacoustics · 2026Article
- Measurement dataset of experimental in-body optical wireless communication test-bed for research purposes.Data in brief · 2025Article
- Scale-equivariant deep model-based optoacoustic image reconstruction.Photoacoustics · 2025Article
- Advancements in tantalum based nanoparticles for integrated imaging and photothermal therapy in cancer management.RSC advances · 2024Review
- Tutorial on phantoms for photoacoustic imaging applications.Journal of biomedical optics · 2024Review
- Tutorial on methods for estimation of optical absorption and scattering properties of tissue.Journal of biomedical optics · 2024Article
- Development of an anatomical breast phantom from polyvinyl chloride plastisol with lesions of various shape, elasticity and echogenicity for teaching ultrasound examination.International journal of computer assisted radiology and surgery · 2024Article
- Phantoms for evaluating the impact of skin pigmentation on photoacoustic imaging and oximetry performance.Biomedical optics express · 2023Article
- Review of imaging test phantoms.Journal of biomedical optics · 2023Review
- Flexible array transducer for photoacoustic-guided interventions: phantom andBiomedical optics express · 2023Article
- Photoacoustic imaging phantoms for assessment of object detectability and boundary buildup artifacts.Photoacoustics · 2022Article
- Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery.Biomedical optics express · 2022Article
- Criteria for the design of tissue-mimicking phantoms for the standardization of biophotonic instrumentation.Nature biomedical engineering · 2022Review
- Tissue-mimicking phantoms for performance evaluation of photoacoustic microscopy systems.Biomedical optics express · 2022Article
- Transfontanelle photoacoustic imaging: ultrasound transducer selection analysis.Biomedical optics express · 2022Article
- Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.Journal of biomedical optics · 2021Review
- Model-based optical and acoustical compensation for photoacoustic tomography of heterogeneous mediums.Photoacoustics · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Established medical imaging technologies such as magnetic resonance imaging and computed tomography rely on well-validated tissue-simulating phantoms for standardized testing of device image quality. The availability of high-quality phantoms for optical-acoustic diagnostics such as photoacoustic tomography (PAT) will facilitate standardization and clinical translation of these emerging approaches. Materials used in prior PAT phantoms do not provide a suitable combination of long-term stability and realistic acoustic and optical properties. Therefore, we have investigated the use of custom polyvinyl chloride plastisol (PVCP) formulations for imaging phantoms and identified a dual-plasticizer approach that provides biologically relevant ranges of relevant properties. Speed of sound and acoustic attenuation were determined over a frequency range of 4 to 9 MHz and optical absorption and scattering over a wavelength range of 400 to 1100 nm. We present characterization of several PVCP formulations, including one designed to mimic breast tissue. This material is used to construct a phantom comprised of an array of cylindrical, hemoglobin-filled inclusions for evaluation of penetration depth. Measurements with a custom near-infrared PAT imager provide quantitative and qualitative comparisons of phantom and tissue images. Results indicate that our PVCP material is uniquely suitable for PAT system image quality evaluation and may provide a practical tool for device validation and intercomparison.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.