Evidence map›Paper›PMID 26886454›Full record

ArticleSurgical endoscopy2016

When is mesh fixation in TAPP-repair of primary inguinal hernia repair necessary? The register-based analysis of 11,230 cases.

F Mayer, H Niebuhr, M Lechner, A Dinnewitzer, G Köhler, M Hukauf, R H Fortelny, R Bittner, F Köckerling

2 registry-linked trialsAbstract read
In one paragraph

Article in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 37 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02781870 narecruitingnot on this map

Randomized Single-center Study on Laparoscopic Groin Hernia Repair by a 3D ENDOLAP Visible With and Without LiquiBand Fix 8 Mesh Fixation

TypeinterventionalSponsorAlgemeen Ziekenhuis Maria MiddelaresRan2016 to 2027Enrolled100ConditionsHernia, RecurrenceArmsLiquiBand Fix8 glue fixation, No-fixation
NCT05678465 nacompletednot on this mapstarted 2023, after this paper: background citation

MEsh FIxation in Laparoendoscopic Repair of Large M3 Inguinal Hernias - Multicenter, Double-blinded, Randomized Controlled Trial.

TypeinterventionalSponsorSwissmed HospitalRan2023 to 2024Enrolled204ConditionsHernia, Inguinal, Hernia, Direct InguinalArmsNon-fixation of the mesh, Fixation of the mesh
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Transabdominal preperitoneal (TAPP) repair for emergency groin hernia: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2024
    Pooled it
  3. Pooled it
  4. International guidelines for groin hernia management.Hernia : the journal of hernias and abdominal wall surgery · 2018
    Guideline
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Article
  9. No mesh fixation versus mesh fixation in laparoscopic groin hernia repair.The Cochrane database of systematic reviews · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

F MayerDepartment of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria. f.mayer@salk.at.
H NiebuhrHanse Hernia Center, Hamburg, Germany.
M LechnerDepartment of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria.
A DinnewitzerDepartment of Surgery, Paracelsus Medical University, Müllner Hauptstrasse 48, 5020, Salzburg, Austria.
G KöhlerDepartment of General and Visceral Surgery, Sisters of Charity Hospital, Linz, Austria.
M HukaufStatConsult GmbH, Magdeburg, Germany.
R H FortelnyDepartment of General, Visceral and Oncological Surgery, Wilhelminenspital, Vienna, Austria.
R BittnerHernia Center, Winghofer Medicum, Rottenburg am Neckar, Germany.
F KöckerlingDepartment of Surgery and Center of Minimally Invasive Surgery, Academic Teaching Hospital of Charité Medical School, Vivantes Hospital Spandau, Neue Bergstrasse 6, 13585, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whereas for TEP the guidelines do not recommend mesh fixation on the basis of meta-analyses regardless of the defect size, for TAPP mesh fixation can be omitted only up to a defect size of 3 cm because of the paucity of studies on this topic. Hence, this study now seeks to explore this subject on the basis of prospective data from the Herniamed Hernia Registry. In the period September 01, 2009, to January 31, 2014, 11,228 male patients were operated on with the TAPP technique for a primary unilateral inguinal hernia and were followed up for 1 year. Mesh fixation was used for 7422 (66.1 %) of these patients and no mesh fixation for 3806 patients (33.9 %). Unadjusted analysis did not find any significant difference in the recurrence rate (0.88 % with fixation vs. 1.1 % without fixation; p = 0.259). Multivariable analysis of all potential influence factors (age, ASA, BMI, risk factors, defect size, mesh fixation, localization of defect, mesh size) did not identify any factor that impacted recurrence on 1-year follow-up. Only for medial and combined defect localization versus lateral localization was a highly significant effect identified (p < 0.001). With mesh fixation and larger mesh size, it was possible to significantly reduce the recurrence rate for larger medial hernias in this series (p = 0.046). For TAPP repair of an inguinal hernia, mesh fixation is not necessary in a significant number of patients. Patients with a medial and combined hernia are at higher risk of recurrence. In the patient series analyzed, it was possible to significantly reduce the recurrence rate with mesh fixation and larger mesh size for medial defects.

Indexed as

RegistriesSurgical MeshAdultAgedHernia, InguinalHerniorrhaphyHumansLaparoscopyMaleMiddle AgedProspective StudiesRecurrenceTreatment OutcomeInguinal herniaMedial herniaMesh fixationRecurrenceTAPP

Identifiers

PMID26886454
PMCPMC5009149

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.