Evidence map›Paper›PMID 26886232›Full record

ReviewCurrent genetics2016

Nitric oxide in fungi: is there NO light at the end of the tunnel?

David Cánovas, Jose F Marcos, Ana T Marcos, Joseph Strauss

Open access · hybridAbstract readReview
In one paragraph

Review in Current genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
9.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 100 citations in OpenAlex.

  1. Article
  2. Metabolic modulation of TCA cycle bySynthetic and systems biotechnology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. The Expanding Mycovirome ofJournal of fungi (Basel, Switzerland) · 2024
    Review
  9. Article
  10. Impact of Nitric Oxide-Release Kinetics on Antifungal Activity.Journal of fungi (Basel, Switzerland) · 2024
    Article
  11. Nitric Oxide in Fungi: Production and Function.Journal of fungi (Basel, Switzerland) · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. The aerotaxis ofFrontiers in cell and developmental biology · 2023
    Article
  18. Article
  19. Article
  20. A Novel De NovoGenes · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

David CánovasDepartment of Genetics, Faculty of Biology, University of Sevilla, Seville, Spain. davidc@us.es.ORCID http://orcid.org/0000-0002-7293-7332
Jose F MarcosDepartment of Food Science, Institute of Agrochemistry and Food Technology (IATA), CSIC, Valencia, Spain.
Ana T MarcosDepartment of Genetics, Faculty of Biology, University of Sevilla, Seville, Spain.
Joseph StraussDivision of Microbial Genetics and Pathogen Interactions, Department of Applied Genetics and Cell Biology, University of Natural Resources and Life Sciences (BOKU), Bioresources Campus Tulln, Vienna, Austria.
Universidad de Sevilla · ESBOKU University · ATInstituto de Agroquímica y Tecnología de Alimentos · ES

Funding

Austrian Science Fund FWF M 1693
6 · The paper itself

Abstract

Nitric oxide (NO) is a remarkable gaseous molecule with multiple and important roles in different organisms, including fungi. However, the study of the biology of NO in fungi has been hindered by the lack of a complete knowledge on the different metabolic routes that allow a proper NO balance, and the regulation of these routes. Fungi have developed NO detoxification mechanisms to combat nitrosative stress, which have been mainly characterized by their connection to pathogenesis or nitrogen metabolism. However, the progress on the studies of NO anabolic routes in fungi has been hampered by efforts to disrupt candidate genes that gave no conclusive data until recently. This review summarizes the different roles of NO in fungal biology and pathogenesis, with an emphasis on the alternatives to explain fungal NO production and the recent findings on the involvement of nitrate reductase in the synthesis of NO and its regulation during fungal development.

Indexed as

FungiHomeostasisHost-Pathogen InteractionsMycosesNitric OxideOxidation-ReductionNitric OxideAspergillusDevelopmentFlavohemoglobinFungal pathogensNitrate reductaseNitric oxide

Identifiers

PMID26886232
PMCPMC4929157
OpenAlexW2284711185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.