Evidence map›Paper›PMID 26885961›Full record

ArticleAmerican journal of public health2016

Evaluating Public Health Interventions: 2. Stepping Up to Routine Public Health Evaluation With the Stepped Wedge Design.

Donna Spiegelman

Abstract read
In one paragraph

Article in American journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  6. Navigating grey areas in HIV and mental health implementation science.Journal of the International AIDS Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Donna SpiegelmanDonna Spiegelman is with the Departments of Epidemiology, Biostatistics, Nutrition, and Global Health, Harvard T.H. Chan School of Public Health, Boston, MA (e-mail: stdls@hsph.harvard.edu ). Reprints can be ordered at http://www.ajph.org by clicking the "Reprints" link.

Funding

Comprehensive Translational Science Analytics Tools for the Global Health AgendaDP1ES025459 · NIEHS · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2018
$4.1M
New Methods for the design and evaluation of large HIV prevention interventionsR01AI112339 · NIAID · YALE UNIVERSITY · PI SPIEGELMAN, DONNA L · 2014 to 2017
$2.7M
NCCDPHP CDC HHS DP1ES025459NIAID NIH HHS R01 AI112339NIEHS NIH HHS DP1 ES025459
6 · The paper itself

Abstract

In a stepped wedge design (SWD), an intervention is rolled out in a staggered manner over time, in groups of experimental units, so that by the end, all units experience the intervention. For example, in the MaxART study, the date at which to offer universal antiretroviral therapy to otherwise ineligible clients is being randomly assigned in nine "steps" of four months duration so that after three years, all 14 facilities in northern and central Swaziland will be offering early treatment. In the common alternative, the cluster randomized trial (CRT), experimental units are randomly allocated on a single common start date to the interventions to be compared. Often, the SWD is more feasible than the CRT, both for practical and ethical reasons, but takes longer to complete. The SWD permits both within- and between- unit comparisons, while the CRT only allows between-unit comparisons. Thus, confounding bias with respect to time-invariant factors tends to be lower in an SWD than a CRT, but the SWD cannot as readily control for confounding by time-varying factors. SWDs have generally more statistical power than CRTs, especially as the intraunit correlation and the number of participants within unit increases. Software for both designs are available, although for a more limited set of SWD scenarios.

Indexed as

Research DesignAnti-Retroviral AgentsBiasEfficiency, OrganizationalEswatiniHIV InfectionsHumansPublic HealthRandomized Controlled Trials as TopicReproducibility of ResultsSoftwareTime FactorsAnti-Retroviral Agents

Identifiers

PMID26885961
PMCPMC4815956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.