Evidence map›Paper›PMID 26885806›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2016

Trends in Serosorting and the Association With HIV/STI Risk Over Time Among Men Who Have Sex With Men.

Christine M Khosropour, Julia C Dombrowski, Fred Swanson, Roxanne P Kerani, David A Katz, Lindley A Barbee, James P Hughes, Lisa E Manhart, Matthew R Golden

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christine M KhosropourDepartments of *Epidemiology; †Medicine; ‡Biostatistics; §Global Health, University of Washington, Seattle, WA; ‖Public Health-Seattle and King County HIV/STD Program, Seattle, WA; and ¶Gay City Health Project, Seattle, WA.
Julia C Dombrowski
Fred Swanson
Roxanne P Kerani
David A Katz
Lindley A Barbee
James P Hughes
Lisa E Manhart
Matthew R Golden

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
Characterizing Extragenital Gonorrhea and Chlamydia: Natural History & HIV ImpactK23AI113185 · NIAID · UNIVERSITY OF WASHINGTON · PI BARBEE, LINDLEY · 2014 to 2018
$903k
Clinic and Population-Based Approaches to Retention in HIV CareK23MH090923 · NIMH · UNIVERSITY OF WASHINGTON · PI DOMBROWSKI, JULIA COOK · 2010 to 2014
$657k
NIAID NIH HHS K23 AI113185NIAID NIH HHS P30 AI027757NIAID NIH HHS T32 AI007140NIMH NIH HHS K23 MH090923NIMH NIH HHS L30 MH095060
6 · The paper itself

Abstract

backgroundSerosorting among men who have sex with men (MSM) is common, but recent data to describe trends in serosorting are limited. How serosorting affects population-level trends in HIV and other sexually transmitted infection (STI) risk is largely unknown.

methodsWe collected data as part of routine care from MSM attending a sexually transmitted disease clinic (2002-2013) and a community-based HIV/sexually transmitted disease testing center (2004-2013) in Seattle, WA. MSM were asked about condom use with HIV-positive, HIV-negative, and unknown-status partners in the prior 12 months. We classified behaviors into 4 mutually exclusive categories: no anal intercourse (AI); consistent condom use (always used condoms for AI); serosorting [condom-less anal intercourse (CAI) only with HIV-concordant partners]; and nonconcordant CAI (CAI with HIV-discordant/unknown-status partners; NCCAI).

resultsBehavioral data were complete for 49,912 clinic visits. Serosorting increased significantly among both HIV-positive and HIV-negative men over the study period. This increase in serosorting was concurrent with a decrease in NCCAI among HIV-negative MSM, but a decrease in consistent condom use among HIV-positive MSM. Adjusting for time since last negative HIV test, the risk of testing HIV positive during the study period decreased among MSM who reported NCCAI (7.1%-2.8%; P= 0.02), serosorting (2.4%-1.3%; P = 0.17), and no CAI (1.5%-0.7%; P = 0.01). Serosorting was associated with a 47% lower risk of testing HIV positive compared with NCCAI (adjusted prevalence ratio = 0.53; 95% confidence interval: 0.45 to 0.62).

conclusionsBetween 2002 and 2013, serosorting increased and NCCAI decreased among Seattle MSM. These changes paralleled a decline in HIV test positivity among MSM.

Indexed as

Homosexuality, MaleAdultCondomsHIV SeropositivityHIV SerosortingHumansMaleMiddle AgedPrevalenceRisk-TakingSexual BehaviorSexually Transmitted DiseasesSexual PartnersWashington

Identifiers

PMID26885806
PMCPMC4866874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.