Evidence map›Paper›PMID 26885758›Full record

ArticlePediatric research2016

Selenium status during pregnancy and child psychomotor development-Polish Mother and Child Cohort study.

Kinga Polanska, Anna Krol, Wojciech Sobala, Jolanta Gromadzinska, Renata Brodzka, Gemma Calamandrei, Flavia Chiarotti, Wojciech Wasowicz, Wojciech Hanke

Open access · hybridAbstract read
In one paragraph

Article in Pediatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Evaluation of nutrients in bread: a systematic review.Journal of health, population, and nutrition · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Current understanding of essential trace elements in intrahepatic cholestasis of pregnancy.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Scientific opinion on the tolerable upper intake level for selenium.EFSA journal. European Food Safety Authority · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Prenatal Metal Exposures and Infants' Developmental Outcomes in a Navajo Population.International journal of environmental research and public health · 2021
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kinga PolanskaDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
Anna KrolDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
Wojciech SobalaDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
Jolanta GromadzinskaDepartment of Biological and Environmental Monitoring, Nofer Institute of Occupational Medicine, Lodz, Poland.
Renata BrodzkaDepartment of Biological and Environmental Monitoring, Nofer Institute of Occupational Medicine, Lodz, Poland.
Gemma CalamandreiUnit of Neurotoxicology and Neuroendocrinology, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy.
Flavia ChiarottiUnit of Neurotoxicology and Neuroendocrinology, Department of Cell Biology and Neuroscience, Istituto Superiore di Sanità, Rome, Italy.
Wojciech WasowiczDepartment of Biological and Environmental Monitoring, Nofer Institute of Occupational Medicine, Lodz, Poland.
Wojciech HankeDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
Nofer Institute of Occupational Medicine · PLIstituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe studies on the impact of selenium (Se) levels in different pregnancy periods on child psychomotor functions are limited. The aim of this study was to evaluate the impact of prenatal Se on child neurodevelopment.

methodsThe study population consisted of 410 mother-child pairs from Polish Mother and Child Cohort. Se levels were measured in each trimester of pregnancy, at delivery, and in cord blood by graphite furnace atomic absorption spectrometry. Psychomotor development was assessed in children at the age of 1 and 2 y using the Bayley Scales of Infant and Toddler Development.

resultsPlasma Se levels decreased through pregnancy (from 48.3 ± 10.6 µg/l in the first trimester to 38.4 ± 11.8 µg/l at delivery; P < 0.05). A statistically significant positive association between Se levels in the first trimester of pregnancy and motor development (β = 0.2, P = 0.002) at 1 y of age, and language development (β = 0.2, P = 0.03) at 2 y of age was observed. The positive effect of Se levels on cognitive score at 2 y of age was of borderline significance (β = 0.2, P = 0.05).

conclusionPrenatal selenium status was associated with child psychomotor abilities within the first years of life. Further epidemiological and preclinical studies are needed to confirm the association and elucidate the underlying mechanisms of these effects.

Indexed as

Maternal Nutritional Physiological PhenomenaPsychomotor PerformanceAdultBirth WeightChild DevelopmentCohort StudiesEnvironmental ExposureFemaleFetal BloodHumansInfantLanguage DevelopmentMaternal AgeMothersPolandPregnancySelenium

Identifiers

PMID26885758
PMCPMC4899820
OpenAlexW2276480169

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.