Evidence map›Paper›PMID 26885674›Full record

ArticleEmerging infectious diseases2016

Global Progress and Challenges in Implementing New Medications for Treating Multidrug-Resistant Tuberculosis.

Jennifer Furin, Grania Brigden, Erica Lessem, Michael Rich, Laura Vaughan, Sharonann Lynch

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. We Are Underprepared for Bedaquiline Resistance: A Call for Clinical and Programmatic Readiness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  2. Article
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  4. Article
  5. Article
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  7. Article
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  9. Review
  10. Integration of drug safety monitoring in tuberculosis treatment programmes: country experiences.European respiratory review : an official journal of the European Respiratory Society · 2019
    Review
  11. Article
  12. Article
  13. Review
  14. Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Frontiers in cellular and infection microbiology · 2018
    Review
  15. Article
  16. Article
  17. Examples of bedaquiline introduction for the management of multidrug-resistant tuberculosis in five countries.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2017
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer Furin
Grania Brigden
Erica Lessem
Michael Rich
Laura Vaughan
Sharonann Lynch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new drugs-bedaquiline and delamanid-have recently been approved by stringent regulatory authorities to treat multidrug-resistant tuberculosis (TB) and recommended by the World Health Organization for use under defined programmatic conditions. Introducing the medications in TB programs worldwide has not kept pace with the need for these drugs. In response, the DR-TB STAT (Drug-Resistant TB Scale-up Treatment Action Team) task force was formed in April 2015 to monitor progress and help overcome challenges. Information was collected from multiple sources and assessed monthly. Some progress has been made in introducing bedaquiline: as of October 2015, a total of 1,258 persons were on the medication under programmatic conditions. For delamanid, >100 patients, but few under programmatic conditions, have received the medication. Coordinated global action might help assist making these medications accessible for persons who need them most.

Indexed as

Antitubercular AgentsDiarylquinolinesDrug ApprovalHumansNitroimidazolesOxazolesTuberculosis, Multidrug-ResistantAntitubercular AgentsbedaquilineDiarylquinolinesNitroimidazolesOPC-67683Oxazolesantimicrobial resistancebacteriabedaquilinedelamaniddrug-resistant TBglobal progressMycobacterium tuberculosis and other mycobacteria

Identifiers

PMID26885674
PMCPMC4766879

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.