ArticleJournal of diabetes research2016
Vitamin D Deficiency Is Not Associated with Diabetic Retinopathy or Maculopathy.
Article in Journal of diabetes research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Association between serum vitamin D levels and the risk of diabetic retinopathy: a meta-analysis.Frontiers in medicine · 2026Pooled it
- Vitamin D and Ocular Diseases: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Pooled it
- The Association between Vitamin D Deficiency and Diabetic Retinopathy in Type 2 Diabetes: A Meta-Analysis of Observational Studies.Nutrients · 2017Pooled it
- Improvement in Neuropathy Specific Quality of Life in Patients with Diabetes after Vitamin D Supplementation.Journal of diabetes research · 2017Trial
- Association of vitamin D3 and diabetic retinopathy in US adults: A cross-sectional study.Medicine · 2026Article
- Vitamin D status and its association with diabetic complications in type 2 diabetes mellitus: A case-control study.Nutrition and health · 2026Article
- Vitamin D supplementation in diabetic retinopathy: an optical coherence tomography angiography study of changes in macular perfusion.International journal of retina and vitreous · 2026Article
- Impact of Vitamin D Deficiency and VDRFood science & nutrition · 2025Article
- Impact of vitamin D on glycemic control and microvascular complications in type 2 diabetes: A cross-sectional study.PloS one · 2025Article
- Gender-specific association between circulating 25-hydroxyvitamin D levels and diabetic retinopathy in patients with type 2 diabetes mellitus.Frontiers in endocrinology · 2025Article
- Vitamin D Deficiency as a Risk Factor for Diabetic Retinopathy: A Systematic Review and Meta-Analysis.Biomedicines · 2024Review
- Review
- Vitamin D deficiency and the risk of diabetic retinopathy in patients with type 2 diabetes in Tibet: a cross-sectional analysis.BMC endocrine disorders · 2024Article
- Assessment of vitamin D status and vitamin D receptor polymorphism in Egyptian children with Type 1 diabetes.Journal, genetic engineering & biotechnology · 2024Article
- Vitamin D levels and risk of ocular disorders: insights from bidirectional and multivariable Mendelian randomization analysis.Frontiers in medicine · 2024Article
- The Roles of Vitamins in Diabetic Retinopathy: A Narrative Review.Journal of clinical medicine · 2022Review
- Hypovitaminosis D in patients with type 2 diabetes: risk factors and association with glycemic control and established microvascular complicationsRevista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022Article
- Associations between vitamin D status and sight threatening and non-sight threatening diabetic retinopathy: a systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2022Review
- Vitamin D Deficiency Is Significantly Associated with Retinopathy in Type 2 Diabetes Mellitus: A Case-Control Study.Nutrients · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExperimental and clinical studies suggest a possible association between vitamin D deficiency and both diabetic retinopathy and maculopathy.
methodsWe have performed a cross-sectional study in adults with types 1 and 2 diabetes mellitus. The relationship between the presence and severity of diabetic retinopathy and maculopathy with serum 25-hydroxyvitamin D concentration was evaluated using logistic regression analyses in the presence of demographic and clinical covariates.
results657 adults with diabetes were stratified based on retinopathy grading: No Diabetic Retinopathy (39%), Background Diabetic Retinopathy (37%), Preproliferative Diabetic Retinopathy (21%), and Proliferative Diabetic Retinopathy (3%), respectively. There were no differences in serum 25-hydroxyvitamin D concentrations (25(OH)D) between the groups (15.3 ± 9.0 versus 16.4 ± 10.5 versus 15.9 ± 10.4 versus 15.7 ± 8.5 ng/mL, P = NS). Logistic regression analysis demonstrated no statistically significant relationship between the severity of retinopathy and serum 25(OH)D. Furthermore, there was no difference in serum 25(OH)D between those with (n = 94, 14%) and those without (n = 563, 86%) Diabetic Maculopathy (16.2 ± 10.0 versus 15.8 ± 9.8, P = NS) and no relationship was demonstrated by logistic regression analyses between the two variables.
conclusionsThis study has found no association between serum 25(OH)D and the presence and severity of diabetic retinopathy or maculopathy.
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