ReviewBioMed research international2016
New Ti-Alloys and Surface Modifications to Improve the Mechanical Properties and the Biological Response to Orthopedic and Dental Implants: A Review.
Review in BioMed research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Cytotoxic effects of submicron- and nano-scale titanium debris released from dental implants: an integrative review.Clinical oral investigations · 2021Pooled it
- Early Bone Formation around Immediately Loaded Transitional Implants Inserted in the Human Posterior Maxilla: The Effects of Fixture Design and Surface.BioMed research international · 2017Trial
- Tapered, Double-Lead Threads Single Implants Placed in Fresh Extraction Sockets and Healed Sites of the Posterior Jaws: A Multicenter Randomized Controlled Trial with 1 to 3 Years of Follow-Up.BioMed research international · 2017Trial
- Machine Learning and Artificial Intelligence in Metallic Orthopedic Implant Development: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Hybrid Bioceramic: A Synergistic Platform for Structural Reinforcement and Bioelectric Stimulation Toward Smart Medical Devices.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Effect of internal connection parameters on the fatigue limit of narrow-diameter implants - a finite element study.Journal of dentistry · 2026Article
- AI-Assisted Design and Evaluation of SLM-Ti64 Implants for Enhanced Bone Regeneration.Advanced healthcare materials · 2025Article
- Article
- Fatigue Resistance of Customized Implant-Supported Restorations.Materials (Basel, Switzerland) · 2025Article
- Screening dental implant design parameters for effect on the fatigue limit of reduced-diameter implants.Dental materials : official publication of the Academy of Dental Materials · 2025Article
- Functionalization of collagen fiber with nano-islands of silver via atomic layer deposition to promote bone healing.Heliyon · 2025Article
- Microstructure and Micro-Mechanical Properties of Thermally Sprayed HA-TiOMaterials (Basel, Switzerland) · 2025Article
- Article
- Preparation of CuOpen life sciences · 2024Article
- Cheminformatics-Based Design and Synthesis of Hydroxyapatite/Collagen Nanocomposites for Biomedical Applications.Polymers · 2023Article
- Impact of Beam Deflection Geometry on the Surface Architecture and Mechanical Properties of Electron-Beam-Modified TC4 Titanium Alloy.Materials (Basel, Switzerland) · 2023Article
- Influence of Aluminum and Copper on Mechanical Properties of Biocompatible Ti-Mo Alloys: A Simulation-Based Investigation.Micromachines · 2023Article
- Surface Modification of Biomedical Ti-18Zr-15Nb Alloy by Atomic Layer Deposition and Ag Nanoparticles Decoration.Journal of functional biomaterials · 2023Article
- Surface Characterization of New β Ti-25Ta-Zr-Nb Alloys Modified by Micro-Arc Oxidation.Materials (Basel, Switzerland) · 2023Article
- The Effects of Titanium Dioxide Nanoparticles on Osteoblasts Mineralization: A Comparison between 2D and 3D Cell Culture Models.Nanomaterials (Basel, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium implants are widely used in the orthopedic and dentistry fields for many decades, for joint arthroplasties, spinal and maxillofacial reconstructions, and dental prostheses. However, despite the quite satisfactory survival rates failures still exist. New Ti-alloys and surface treatments have been developed, in an attempt to overcome those failures. This review provides information about new Ti-alloys that provide better mechanical properties to the implants, such as superelasticity, mechanical strength, and corrosion resistance. Furthermore, in vitro and in vivo studies, which investigate the biocompatibility and cytotoxicity of these new biomaterials, are introduced. In addition, data regarding the bioactivity of new surface treatments and surface topographies on Ti-implants is provided. The aim of this paper is to discuss the current trends, advantages, and disadvantages of new titanium-based biomaterials, fabricated to enhance the quality of life of many patients around the world.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.